Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
Identifieur interne : 004842 ( Main/Exploration ); précédent : 004841; suivant : 004843Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
Auteurs : Ashley H. Beecham [États-Unis] ; Nikolaos A. Patsopoulos [États-Unis] ; Dionysia K. Xifara [Royaume-Uni] ; Mary F. Davis [États-Unis] ; Anu Kemppinen [Royaume-Uni] ; Chris Cotsapas [États-Unis] ; Tejas S. Shahi [Royaume-Uni] ; Chris Spencer [Royaume-Uni] ; David Booth [Australie] ; An Goris [Belgique] ; Annette Oturai [Danemark] ; Janna Saarela [Finlande] ; Bertrand Fontaine [France] ; Bernhard Hemmer [Allemagne] ; Claes Martin [Suède] ; Frauke Zipp [Allemagne] ; Sandra D Lfonso [Italie] ; Filippo Martinelli-Boneschi [Italie] ; Bruce Taylor [Australie] ; Hanne F. Harbo [Norvège] ; Ingrid Kockum [Suède] ; Jan Hillert [Suède] ; Tomas Olsson [Suède] ; Maria Ban [Royaume-Uni] ; Jorge R. Oksenberg [États-Unis] ; Rogier Hintzen [Pays-Bas] ; Lisa F. Barcellos [États-Unis] ; Cristina Agliardi [Italie] ; Lars Alfredsson [Suède] ; Mehdi Alizadeh [France] ; Carl Anderson [Royaume-Uni] ; Robert Andrews [Royaume-Uni] ; Helle Bach S Ndergaard [Danemark] ; Amie Baker [Royaume-Uni] ; Gavin Band [Royaume-Uni] ; Sergio E. Baranzini [États-Unis] ; Nadia Barizzone [Italie] ; Jeffrey Barrett [Royaume-Uni] ; Céline Bellenguez [Royaume-Uni] ; Laura Bergamaschi [Italie] ; Luisa Bernardinelli [Royaume-Uni] ; Achim Berthele [Allemagne] ; Viola Biberacher [Allemagne] ; Thomas M C. Binder [Allemagne] ; Hannah Blackburn [Royaume-Uni] ; Izaura L. Bomfim [Suède] ; Paola Brambilla [Italie] ; Simon Broadley [Australie] ; Bruno Brochet [France] ; Lou Brundin [Suède] ; Dorothea Buck [Allemagne] ; Helmut Butzkueven [Australie] ; Stacy J. Caillier [États-Unis] ; William Camu [France] ; Wassila Carpentier [France] ; Paola Cavalla [Italie] ; Elisabeth G. Celius [Norvège] ; Irène Coman [France] ; Giancarlo Comi [Italie] ; Lucia Corrado [Italie] ; Leentje Cosemans [Belgique] ; Isabelle Cournu-Rebeix [France] ; Bruce A C. Cree [États-Unis] ; Daniele Cusi [Italie] ; Vincent Damotte [France] ; Gilles Defer [France] ; Silvia R. Delgado [États-Unis] ; Panos Deloukas [Royaume-Uni] ; Alessia Di Sapio [Italie] ; Alexander T. Dilthey [Royaume-Uni] ; Peter Donnelly [Royaume-Uni] ; Bénédicte Dubois [Belgique] ; Martin Duddy [Royaume-Uni] ; Sarah Edkins [Royaume-Uni] ; Irina Elovaara [Finlande] ; Federica Esposito [Italie] ; Nikos Evangelou [Royaume-Uni] ; Barnaby Fiddes [Royaume-Uni] ; Judith Field [Australie] ; Andre Franke [Allemagne] ; Colin Freeman [Royaume-Uni] ; Irene Y. Frohlich [États-Unis] ; Daniela Galimberti [Italie] ; Christian Gieger [Allemagne] ; Pierre-Antoine Gourraud [États-Unis] ; Christiane Graetz [Allemagne] ; Andrew Graham [Royaume-Uni] ; Verena Grummel [Allemagne] ; Clara Guaschino [Italie] ; Athena Hadjixenofontos [États-Unis] ; Hakon Hakonarson [États-Unis] ; Christopher Halfpenny [Royaume-Uni] ; Gillian Hall [Royaume-Uni] ; Per Hall [Suède] ; Anders Hamsten [Suède] ; James Harley [Royaume-Uni] ; Timothy Harrower [Royaume-Uni] ; Clive Hawkins [Royaume-Uni] ; Garrett Hellenthal [Royaume-Uni] ; Charles Hillier [Royaume-Uni] ; Jeremy Hobart [Royaume-Uni] ; Muni Hoshi [Allemagne] ; Sarah E. Hunt [Royaume-Uni] ; Maja Jagodic [Suède] ; Ilijas Jel I [Allemagne, Suisse] ; Angela Jochim [Allemagne] ; Brian Kendall [Royaume-Uni] ; Allan Kermode [Australie] ; Trevor Kilpatrick [Australie] ; Keijo Koivisto [Finlande] ; Ioanna Konidari [États-Unis] ; Thomas Korn [Allemagne] ; Helena Kronsbein [Allemagne] ; Cordelia Langford [Royaume-Uni] ; Malin Larsson [Suède] ; Mark Lathrop [France, Canada] ; Christine Lebrun-Frenay [France] ; Jeannette Lechner-Scott [Australie] ; Michelle H. Lee [États-Unis] ; Maurizio A. Leone [Italie] ; Virpi Lepp [Finlande] ; Giuseppe Liberatore [Italie] ; Benedicte A. Lie [Norvège] ; Christina M. Lill [Allemagne] ; Magdalena Lindén [Suède] ; Jenny Link [Suède] ; Felix Luessi [Allemagne] ; Jan Lycke [Suède] ; Fabio Macciardi [États-Unis, Italie] ; Satu M Nnistö [Finlande] ; Clara P. Manrique [États-Unis] ; Roland Martin [Allemagne, Suisse] ; Vittorio Martinelli [Italie] ; Deborah Mason [Nouvelle-Zélande] ; Gordon Mazibrada [Royaume-Uni] ; Cristin Mccabe [États-Unis] ; Inger-Lise Mero [Norvège] ; Julia Mescheriakova [Pays-Bas] ; Loukas Moutsianas [Royaume-Uni] ; Kjell-Morten Myhr [Norvège] ; Guy Nagels [Belgique] ; Richard Nicholas [Royaume-Uni] ; Petra Nilsson [Suède] ; Fredrik Piehl [Suède] ; Matti Pirinen [Royaume-Uni] ; Siân E. Price [Royaume-Uni] ; Hong Quach [États-Unis] ; Mauri Reunanen [Finlande] ; Wim Robberecht [Belgique] ; Neil P. Robertson [Royaume-Uni] ; Mariaemma Rodegher [Italie] ; David Rog [Royaume-Uni] ; Marco Salvetti [Italie] ; Nathalie C. Schnetz-Boutaud [États-Unis] ; Finn Sellebjerg [Danemark] ; Rebecca C. Selter [Allemagne] ; Catherine Schaefer [États-Unis] ; Sandip Shaunak [Royaume-Uni] ; Ling Shen [États-Unis] ; Simon Shields [Royaume-Uni] ; Volker Siffrin [Allemagne] ; Mark Slee [Australie] ; Per Soelberg Sorensen [Danemark] ; Melissa Sorosina [Italie] ; Mireia Sospedra [Allemagne, Suisse] ; Anne Spurkland [Norvège] ; Amy Strange [Royaume-Uni] ; Emilie Sundqvist [Suède] ; Vincent Thijs [Belgique] ; John Thorpe [Royaume-Uni] ; Anna Ticca [Italie] ; Pentti Tienari [Finlande] ; Cornelia Van Duijn [Pays-Bas] ; Elizabeth M. Visser [Royaume-Uni] ; Steve Vucic [Australie] ; Helga Westerlind [Suède] ; James S. Wiley [Australie] ; Alastair Wilkins [Royaume-Uni] ; James F. Wilson [Royaume-Uni] ; Juliane Winkelmann [Allemagne] ; John Zajicek [Royaume-Uni] ; Eva Zindler [Allemagne] ; Jonathan L. Haines [États-Unis] ; Margaret A. Pericak-Vance [États-Unis] ; Adrian J. Ivinson [États-Unis] ; Graeme Stewart [Australie] ; David Hafler [États-Unis] ; Stephen L. Hauser [États-Unis] ; Alastair Compston [Royaume-Uni] ; Gil Mcvean [Royaume-Uni] ; Philip De Jager [États-Unis] ; Stephen Sawcer [Royaume-Uni] ; Jacob L. Mccauley [États-Unis]Source :
- Nature genetics [ 1061-4036 ] ; 2013.
Abstract
Using the ImmunoChip custom genotyping array, we analysed 14,498 multiple sclerosis subjects and 24,091 healthy controls for 161,311 autosomal variants and identified 135 potentially associated regions (p-value < 1.0 × 10-4). In a replication phase, we combined these data with previous genome-wide association study (GWAS) data from an independent 14,802 multiple sclerosis subjects and 26,703 healthy controls. In these 80,094 individuals of European ancestry we identified 48 new susceptibility variants (p-value < 5.0 × 10-8); three found after conditioning on previously identified variants. Thus, there are now 110 established multiple sclerosis risk variants in 103 discrete loci outside of the Major Histocompatibility Complex. With high resolution Bayesian fine-mapping, we identified five regions where one variant accounted for more than 50% of the posterior probability of association. This study enhances the catalogue of multiple sclerosis risk variants and illustrates the value of fine-mapping in the resolution of GWAS signals.
Url:
DOI: 10.1038/ng.2770
PubMed: 24076602
PubMed Central: 3832895
Affiliations:
- Allemagne, Australie, Belgique, Canada, Danemark, Finlande, France, Italie, Norvège, Nouvelle-Zélande, Pays-Bas, Royaume-Uni, Suisse, Suède, États-Unis
- Angleterre, Angleterre de l'Est, Aquitaine, Basse-Normandie, Bavière, Berlin, Californie, Canton de Zurich, Connecticut, District de Haute-Bavière, Floride, Grand Londres, Hambourg, Hollande-Méridionale, Hovedstaden, Languedoc-Roussillon, Latium, Lombardie, Massachusetts, Midlands de l'Ouest, Nouvelle-Aquitaine, Nouvelle-Galles du Sud, Occitanie (région administrative), Oxfordshire, Pennsylvanie, Piémont, Québec, Rhénanie-Palatinat, Région Bretagne, Région Normandie, Schleswig-Holstein, Svealand, Tennessee, Uusimaa, Victoria (État), Écosse, Île-de-France, Østlandet
- Berlin, Birmingham, Bobigny, Bordeaux, Caen, Cambridge, Copenhague, Hambourg, Helsinki, Kiel, Londres, Mayence, Melbourne, Milan, Montpellier, Montréal, Munich, Oslo, Oxford, Paris, Rennes, Rome, Rotterdam, Stockholm, Sydney, Turin, Zurich, Édimbourg, Évry (Essonne)
- University College de Londres, Université d'Helsinki, Université d'Oxford, Université d'Édimbourg, Université de Cambridge, Université de Melbourne, Université de Sydney, Université technique de Munich
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Le document en format XML
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Shahi</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Spencer, Chris" sort="Spencer, Chris" uniqKey="Spencer C" first="Chris" last="Spencer">Chris Spencer</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement 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xml:lang="fr">Belgique</country><wicri:regionArea>Section of Experimental Neurology, Laboratory for Neuroimmunology, KU Leuven, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Oturai, Annette" sort="Oturai, Annette" uniqKey="Oturai A" first="Annette" last="Oturai">Annette Oturai</name><affiliation wicri:level="3"><nlm:aff id="A16">Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Saarela, Janna" sort="Saarela, Janna" uniqKey="Saarela J" first="Janna" last="Saarela">Janna Saarela</name><affiliation wicri:level="4"><nlm:aff id="A17">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Fontaine, Bertrand" sort="Fontaine, Bertrand" uniqKey="Fontaine B" first="Bertrand" last="Fontaine">Bertrand Fontaine</name><affiliation wicri:level="3"><nlm:aff id="A18">Département de Neurologie, INSERM UMR S 975 CRICM, UPMC, Pitié-Salpêtrière, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Département de Neurologie, INSERM UMR S 975 CRICM, UPMC, Pitié-Salpêtrière, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Hemmer, Bernhard" sort="Hemmer, Bernhard" uniqKey="Hemmer B" first="Bernhard" last="Hemmer">Bernhard Hemmer</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A20">Munich Cluster for Systems Neurology (SyNergy), Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Munich Cluster for Systems Neurology (SyNergy), Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A21">German Competence Network Multiple Sclerosis (KKNMS), Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Competence Network Multiple Sclerosis (KKNMS), Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Martin, Claes" sort="Martin, Claes" uniqKey="Martin C" first="Claes" last="Martin">Claes Martin</name><affiliation wicri:level="3"><nlm:aff id="A22">Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Zipp, Frauke" sort="Zipp, Frauke" uniqKey="Zipp F" first="Frauke" last="Zipp">Frauke Zipp</name><affiliation wicri:level="3"><nlm:aff id="A23">Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz</wicri:regionArea><placeName><region type="land" nuts="2">Rhénanie-Palatinat</region><settlement type="city">Mayence</settlement></placeName></affiliation></author><author><name sortKey="D Lfonso, Sandra" sort="D Lfonso, Sandra" uniqKey="D Lfonso S" first="Sandra" last="D Lfonso">Sandra D Lfonso</name><affiliation wicri:level="1"><nlm:aff id="A24">Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara</wicri:regionArea><wicri:noRegion>Novara</wicri:noRegion></affiliation></author><author><name sortKey="Martinelli Boneschi, Filippo" sort="Martinelli Boneschi, Filippo" uniqKey="Martinelli Boneschi F" first="Filippo" last="Martinelli-Boneschi">Filippo Martinelli-Boneschi</name><affiliation wicri:level="3"><nlm:aff id="A25">Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A26">Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Taylor, Bruce" sort="Taylor, Bruce" uniqKey="Taylor B" first="Bruce" last="Taylor">Bruce Taylor</name><affiliation wicri:level="1"><nlm:aff id="A27">Menzies Research Institute Tasmania, University of Tasmania, Tasmania, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Menzies Research Institute Tasmania, University of Tasmania, Tasmania</wicri:regionArea><wicri:noRegion>Tasmania</wicri:noRegion></affiliation></author><author><name sortKey="Harbo, Hanne F" sort="Harbo, Hanne F" uniqKey="Harbo H" first="Hanne F" last="Harbo">Hanne F. Harbo</name><affiliation wicri:level="3"><nlm:aff id="A28">Department of Neurology, Oslo University Hospital, Ullevål, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Neurology, Oslo University Hospital, Ullevål, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A29">University of Oslo, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Kockum, Ingrid" sort="Kockum, Ingrid" uniqKey="Kockum I" first="Ingrid" last="Kockum">Ingrid Kockum</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Hillert, Jan" sort="Hillert, Jan" uniqKey="Hillert J" first="Jan" last="Hillert">Jan Hillert</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Olsson, Tomas" sort="Olsson, Tomas" uniqKey="Olsson T" first="Tomas" last="Olsson">Tomas Olsson</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Ban, Maria" sort="Ban, Maria" uniqKey="Ban M" first="Maria" last="Ban">Maria Ban</name><affiliation wicri:level="4"><nlm:aff id="A9">Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Oksenberg, Jorge R" sort="Oksenberg, Jorge R" uniqKey="Oksenberg J" first="Jorge R" last="Oksenberg">Jorge R. Oksenberg</name><affiliation wicri:level="2"><nlm:aff id="A31">Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Hintzen, Rogier" sort="Hintzen, Rogier" uniqKey="Hintzen R" first="Rogier" last="Hintzen">Rogier Hintzen</name><affiliation wicri:level="3"><nlm:aff id="A32">Department of Neurology, MS Center ErasMS, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, MS Center ErasMS, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Barcellos, Lisa F" sort="Barcellos, Lisa F" uniqKey="Barcellos L" first="Lisa F" last="Barcellos">Lisa F. Barcellos</name><affiliation wicri:level="2"><nlm:aff id="A33">Division of Epidemiology, Genetic Epidemiology and Genomics Laboratory, School of Public Health, University of California, Berkeley, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology, Genetic Epidemiology and Genomics Laboratory, School of Public Health, University of California, Berkeley, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A34">California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A35">Kaiser Permanente Division of Research, Oakland, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Kaiser Permanente Division of Research, Oakland, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Agliardi, Cristina" sort="Agliardi, Cristina" uniqKey="Agliardi C" first="Cristina" last="Agliardi">Cristina Agliardi</name><affiliation wicri:level="3"><nlm:aff id="A37">Laboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi Foundation ONLUS, IRCCS S. Maria Nascente, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi Foundation ONLUS, IRCCS S. Maria Nascente, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Alfredsson, Lars" sort="Alfredsson, Lars" uniqKey="Alfredsson L" first="Lars" last="Alfredsson">Lars Alfredsson</name><affiliation wicri:level="3"><nlm:aff id="A38">Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Alizadeh, Mehdi" sort="Alizadeh, Mehdi" uniqKey="Alizadeh M" first="Mehdi" last="Alizadeh">Mehdi Alizadeh</name><affiliation wicri:level="3"><nlm:aff id="A39">Université Rennes 1, Rennes, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Université Rennes 1, Rennes</wicri:regionArea><placeName><region type="region">Région Bretagne</region><region type="old region">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Anderson, Carl" sort="Anderson, Carl" uniqKey="Anderson C" first="Carl" last="Anderson">Carl Anderson</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Andrews, Robert" sort="Andrews, Robert" uniqKey="Andrews R" first="Robert" last="Andrews">Robert Andrews</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="S Ndergaard, Helle Bach" sort="S Ndergaard, Helle Bach" uniqKey="S Ndergaard H" first="Helle Bach" last="S Ndergaard">Helle Bach S Ndergaard</name><affiliation wicri:level="3"><nlm:aff id="A16">Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Baker, Amie" sort="Baker, Amie" uniqKey="Baker A" first="Amie" last="Baker">Amie Baker</name><affiliation wicri:level="4"><nlm:aff id="A9">Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Band, Gavin" sort="Band, Gavin" uniqKey="Band G" first="Gavin" last="Band">Gavin Band</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Baranzini, Sergio E" sort="Baranzini, Sergio E" uniqKey="Baranzini S" first="Sergio E" last="Baranzini">Sergio E. Baranzini</name><affiliation wicri:level="2"><nlm:aff id="A31">Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Barizzone, Nadia" sort="Barizzone, Nadia" uniqKey="Barizzone N" first="Nadia" last="Barizzone">Nadia Barizzone</name><affiliation wicri:level="1"><nlm:aff id="A24">Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara</wicri:regionArea><wicri:noRegion>Novara</wicri:noRegion></affiliation></author><author><name sortKey="Barrett, Jeffrey" sort="Barrett, Jeffrey" uniqKey="Barrett J" first="Jeffrey" last="Barrett">Jeffrey Barrett</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Bellenguez, Celine" sort="Bellenguez, Celine" uniqKey="Bellenguez C" first="Céline" last="Bellenguez">Céline Bellenguez</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Bergamaschi, Laura" sort="Bergamaschi, Laura" uniqKey="Bergamaschi L" first="Laura" last="Bergamaschi">Laura Bergamaschi</name><affiliation wicri:level="1"><nlm:aff id="A24">Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara</wicri:regionArea><wicri:noRegion>Novara</wicri:noRegion></affiliation></author><author><name sortKey="Bernardinelli, Luisa" sort="Bernardinelli, Luisa" uniqKey="Bernardinelli L" first="Luisa" last="Bernardinelli">Luisa Bernardinelli</name><affiliation wicri:level="1"><nlm:aff id="A40">Medical Research Council Biostatistics Unit, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council Biostatistics Unit, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Berthele, Achim" sort="Berthele, Achim" uniqKey="Berthele A" first="Achim" last="Berthele">Achim Berthele</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Biberacher, Viola" sort="Biberacher, Viola" uniqKey="Biberacher V" first="Viola" last="Biberacher">Viola Biberacher</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Binder, Thomas M C" sort="Binder, Thomas M C" uniqKey="Binder T" first="Thomas M C" last="Binder">Thomas M C. Binder</name><affiliation wicri:level="3"><nlm:aff id="A41">Department of Transfusion Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Transfusion Medicine, University Medical Center Hamburg-Eppendorf, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Blackburn, Hannah" sort="Blackburn, Hannah" uniqKey="Blackburn H" first="Hannah" last="Blackburn">Hannah Blackburn</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Bomfim, Izaura L" sort="Bomfim, Izaura L" uniqKey="Bomfim I" first="Izaura L" last="Bomfim">Izaura L. Bomfim</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Brambilla, Paola" sort="Brambilla, Paola" uniqKey="Brambilla P" first="Paola" last="Brambilla">Paola Brambilla</name><affiliation wicri:level="3"><nlm:aff id="A25">Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Broadley, Simon" sort="Broadley, Simon" uniqKey="Broadley S" first="Simon" last="Broadley">Simon Broadley</name><affiliation wicri:level="1"><nlm:aff id="A42">School of Medicine, Griffith University, Gold Coast, Queensland, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Medicine, Griffith University, Gold Coast, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Brochet, Bruno" sort="Brochet, Bruno" uniqKey="Brochet B" first="Bruno" last="Brochet">Bruno Brochet</name><affiliation wicri:level="3"><nlm:aff id="A43">CHU Pellegrin, Université Bordeaux 2, Bordeaux, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>CHU Pellegrin, Université Bordeaux 2, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Brundin, Lou" sort="Brundin, Lou" uniqKey="Brundin L" first="Lou" last="Brundin">Lou Brundin</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Buck, Dorothea" sort="Buck, Dorothea" uniqKey="Buck D" first="Dorothea" last="Buck">Dorothea Buck</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Butzkueven, Helmut" sort="Butzkueven, Helmut" uniqKey="Butzkueven H" first="Helmut" last="Butzkueven">Helmut Butzkueven</name><affiliation wicri:level="4"><nlm:aff id="A44">University of Melbourne, Victoria, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>University of Melbourne, Victoria, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A45">Department of Neurology, Box Hill Hospital, Monash University, Victoria, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Neurology, Box Hill Hospital, Monash University, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Caillier, Stacy J" sort="Caillier, Stacy J" uniqKey="Caillier S" first="Stacy J" last="Caillier">Stacy J. Caillier</name><affiliation wicri:level="2"><nlm:aff id="A31">Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Camu, William" sort="Camu, William" uniqKey="Camu W" first="William" last="Camu">William Camu</name><affiliation wicri:level="3"><nlm:aff id="A46">Service de Neurologie, CHRU Montpellier, Montpellier, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, CHRU Montpellier, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Carpentier, Wassila" sort="Carpentier, Wassila" uniqKey="Carpentier W" first="Wassila" last="Carpentier">Wassila Carpentier</name><affiliation wicri:level="3"><nlm:aff id="A47">Plateforme Post-Génomique P3S, UPMC-INSERM, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Plateforme Post-Génomique P3S, UPMC-INSERM, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Cavalla, Paola" sort="Cavalla, Paola" uniqKey="Cavalla P" first="Paola" last="Cavalla">Paola Cavalla</name><affiliation wicri:level="3"><nlm:aff id="A48">Department of Neuroscience, MS Center, Azienda ospedaliera Città della Salute e della Scienza di Torino, Turin, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neuroscience, MS Center, Azienda ospedaliera Città della Salute e della Scienza di Torino, Turin</wicri:regionArea><placeName><settlement type="city">Turin</settlement><region type="région" nuts="2">Piémont</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A49">University of Turin, Turin, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>University of Turin, Turin</wicri:regionArea><placeName><settlement type="city">Turin</settlement><region type="région" nuts="2">Piémont</region></placeName></affiliation></author><author><name sortKey="Celius, Elisabeth G" sort="Celius, Elisabeth G" uniqKey="Celius E" first="Elisabeth G" last="Celius">Elisabeth G. Celius</name><affiliation wicri:level="3"><nlm:aff id="A28">Department of Neurology, Oslo University Hospital, Ullevål, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Neurology, Oslo University Hospital, Ullevål, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Coman, Irene" sort="Coman, Irene" uniqKey="Coman I" first="Irène" last="Coman">Irène Coman</name><affiliation wicri:level="3"><nlm:aff id="A50">Service de Neurologie, Hôpital Avicenne, Bobigny, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, Hôpital Avicenne, Bobigny</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Bobigny</settlement></placeName></affiliation></author><author><name sortKey="Comi, Giancarlo" sort="Comi, Giancarlo" uniqKey="Comi G" first="Giancarlo" last="Comi">Giancarlo Comi</name><affiliation wicri:level="3"><nlm:aff id="A25">Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A26">Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Corrado, Lucia" sort="Corrado, Lucia" uniqKey="Corrado L" first="Lucia" last="Corrado">Lucia Corrado</name><affiliation wicri:level="1"><nlm:aff id="A24">Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara</wicri:regionArea><wicri:noRegion>Novara</wicri:noRegion></affiliation></author><author><name sortKey="Cosemans, Leentje" sort="Cosemans, Leentje" uniqKey="Cosemans L" first="Leentje" last="Cosemans">Leentje Cosemans</name><affiliation wicri:level="1"><nlm:aff id="A15">Section of Experimental Neurology, Laboratory for Neuroimmunology, KU Leuven, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Section of Experimental Neurology, Laboratory for Neuroimmunology, KU Leuven, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Cournu Rebeix, Isabelle" sort="Cournu Rebeix, Isabelle" uniqKey="Cournu Rebeix I" first="Isabelle" last="Cournu-Rebeix">Isabelle Cournu-Rebeix</name><affiliation wicri:level="3"><nlm:aff id="A18">Département de Neurologie, INSERM UMR S 975 CRICM, UPMC, Pitié-Salpêtrière, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Département de Neurologie, INSERM UMR S 975 CRICM, UPMC, Pitié-Salpêtrière, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Cree, Bruce A C" sort="Cree, Bruce A C" uniqKey="Cree B" first="Bruce A C" last="Cree">Bruce A C. Cree</name><affiliation wicri:level="2"><nlm:aff id="A31">Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Cusi, Daniele" sort="Cusi, Daniele" uniqKey="Cusi D" first="Daniele" last="Cusi">Daniele Cusi</name><affiliation wicri:level="3"><nlm:aff id="A51">Department of Health Sciences, San Paolo Hospital and Filarete Foundation, University of Milan, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences, San Paolo Hospital and Filarete Foundation, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Damotte, Vincent" sort="Damotte, Vincent" uniqKey="Damotte V" first="Vincent" last="Damotte">Vincent Damotte</name><affiliation wicri:level="3"><nlm:aff id="A18">Département de Neurologie, INSERM UMR S 975 CRICM, UPMC, Pitié-Salpêtrière, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Département de Neurologie, INSERM UMR S 975 CRICM, UPMC, Pitié-Salpêtrière, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Defer, Gilles" sort="Defer, Gilles" uniqKey="Defer G" first="Gilles" last="Defer">Gilles Defer</name><affiliation wicri:level="3"><nlm:aff id="A52">Service de Neurologie, CHU de Caen and INSERM U 919-GIP Cyceron, Caen, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, CHU de Caen and INSERM U 919-GIP Cyceron, Caen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Basse-Normandie</region><settlement type="city">Caen</settlement></placeName></affiliation></author><author><name sortKey="Delgado, Silvia R" sort="Delgado, Silvia R" uniqKey="Delgado S" first="Silvia R" last="Delgado">Silvia R. Delgado</name><affiliation wicri:level="2"><nlm:aff id="A53">Department of Neurology, Multiple Sclerosis Division, Miller School of Medicine, University of Miami, Miami, Florida, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Multiple Sclerosis Division, Miller School of Medicine, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Deloukas, Panos" sort="Deloukas, Panos" uniqKey="Deloukas P" first="Panos" last="Deloukas">Panos Deloukas</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Di Sapio, Alessia" sort="Di Sapio, Alessia" uniqKey="Di Sapio A" first="Alessia" last="Di Sapio">Alessia Di Sapio</name><affiliation wicri:level="3"><nlm:aff id="A54">Neurologia 2 - CRESM, AOU San Luigi, Orbassano, Turin, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Neurologia 2 - CRESM, AOU San Luigi, Orbassano, Turin</wicri:regionArea><placeName><settlement type="city">Turin</settlement><region type="région" nuts="2">Piémont</region></placeName></affiliation></author><author><name sortKey="Dilthey, Alexander T" sort="Dilthey, Alexander T" uniqKey="Dilthey A" first="Alexander T" last="Dilthey">Alexander T. Dilthey</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Donnelly, Peter" sort="Donnelly, Peter" uniqKey="Donnelly P" first="Peter" last="Donnelly">Peter Donnelly</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Dubois, Benedicte" sort="Dubois, Benedicte" uniqKey="Dubois B" first="Bénédicte" last="Dubois">Bénédicte Dubois</name><affiliation wicri:level="1"><nlm:aff id="A15">Section of Experimental Neurology, Laboratory for Neuroimmunology, KU Leuven, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Section of Experimental Neurology, Laboratory for Neuroimmunology, KU Leuven, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Duddy, Martin" sort="Duddy, Martin" uniqKey="Duddy M" first="Martin" last="Duddy">Martin Duddy</name><affiliation wicri:level="1"><nlm:aff id="A55">Department of Neurology, Royal Victoria Infirmary, Newcastle upon Tyne, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Royal Victoria Infirmary, Newcastle upon Tyne</wicri:regionArea><wicri:noRegion>Newcastle upon Tyne</wicri:noRegion></affiliation></author><author><name sortKey="Edkins, Sarah" sort="Edkins, Sarah" uniqKey="Edkins S" first="Sarah" last="Edkins">Sarah Edkins</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Elovaara, Irina" sort="Elovaara, Irina" uniqKey="Elovaara I" first="Irina" last="Elovaara">Irina Elovaara</name><affiliation wicri:level="1"><nlm:aff id="A56">Department of Neurology, University of Tampere, Medical School, Tampere, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Neurology, University of Tampere, Medical School, Tampere</wicri:regionArea><wicri:noRegion>Tampere</wicri:noRegion></affiliation></author><author><name sortKey="Esposito, Federica" sort="Esposito, Federica" uniqKey="Esposito F" first="Federica" last="Esposito">Federica Esposito</name><affiliation wicri:level="3"><nlm:aff id="A25">Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A26">Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Evangelou, Nikos" sort="Evangelou, Nikos" uniqKey="Evangelou N" first="Nikos" last="Evangelou">Nikos Evangelou</name><affiliation wicri:level="1"><nlm:aff id="A57">Division of Clinical Neurology, Nottingham University Hospital, Nottingham, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Clinical Neurology, Nottingham University Hospital, Nottingham</wicri:regionArea><wicri:noRegion>Nottingham</wicri:noRegion></affiliation></author><author><name sortKey="Fiddes, Barnaby" sort="Fiddes, Barnaby" uniqKey="Fiddes B" first="Barnaby" last="Fiddes">Barnaby Fiddes</name><affiliation wicri:level="4"><nlm:aff id="A9">Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Field, Judith" sort="Field, Judith" uniqKey="Field J" first="Judith" last="Field">Judith Field</name><affiliation wicri:level="4"><nlm:aff id="A58">Florey Institute of Neuroscience and Mental Health, University of Melbourne, Victoria, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Florey Institute of Neuroscience and Mental Health, University of Melbourne, Victoria</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Franke, Andre" sort="Franke, Andre" uniqKey="Franke A" first="Andre" last="Franke">Andre Franke</name><affiliation wicri:level="3"><nlm:aff id="A59">Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Freeman, Colin" sort="Freeman, Colin" uniqKey="Freeman C" first="Colin" last="Freeman">Colin Freeman</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Frohlich, Irene Y" sort="Frohlich, Irene Y" uniqKey="Frohlich I" first="Irene Y" last="Frohlich">Irene Y. Frohlich</name><affiliation wicri:level="2"><nlm:aff id="A2">Department of Neurology, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Brigham & Women’s Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Brigham & Women’s Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Galimberti, Daniela" sort="Galimberti, Daniela" uniqKey="Galimberti D" first="Daniela" last="Galimberti">Daniela Galimberti</name><affiliation wicri:level="3"><nlm:aff id="A60">Department of Pathophysiology and Transplantation, Neurology Unit, University of Milan, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Pathophysiology and Transplantation, Neurology Unit, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A61">Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:aff id="A62">KORAgen, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Institute of Genetic Epidemiology, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>KORAgen, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Institute of Genetic Epidemiology, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Gourraud, Pierre Antoine" sort="Gourraud, Pierre Antoine" uniqKey="Gourraud P" first="Pierre-Antoine" last="Gourraud">Pierre-Antoine Gourraud</name><affiliation wicri:level="2"><nlm:aff id="A31">Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Graetz, Christiane" sort="Graetz, Christiane" uniqKey="Graetz C" first="Christiane" last="Graetz">Christiane Graetz</name><affiliation wicri:level="3"><nlm:aff id="A23">Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz</wicri:regionArea><placeName><region type="land" nuts="2">Rhénanie-Palatinat</region><settlement type="city">Mayence</settlement></placeName></affiliation></author><author><name sortKey="Graham, Andrew" sort="Graham, Andrew" uniqKey="Graham A" first="Andrew" last="Graham">Andrew Graham</name><affiliation wicri:level="1"><nlm:aff id="A63">Department of Clinical Neurology, The Ipswich Hospital NHS Trust, Ipswich, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurology, The Ipswich Hospital NHS Trust, Ipswich</wicri:regionArea><wicri:noRegion>Ipswich</wicri:noRegion></affiliation></author><author><name sortKey="Grummel, Verena" sort="Grummel, Verena" uniqKey="Grummel V" first="Verena" last="Grummel">Verena Grummel</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Guaschino, Clara" sort="Guaschino, Clara" uniqKey="Guaschino C" first="Clara" last="Guaschino">Clara Guaschino</name><affiliation wicri:level="3"><nlm:aff id="A25">Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A26">Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Hadjixenofontos, Athena" sort="Hadjixenofontos, Athena" uniqKey="Hadjixenofontos A" first="Athena" last="Hadjixenofontos">Athena Hadjixenofontos</name><affiliation wicri:level="2"><nlm:aff id="A1">John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Hakonarson, Hakon" sort="Hakonarson, Hakon" uniqKey="Hakonarson H" first="Hakon" last="Hakonarson">Hakon Hakonarson</name><affiliation wicri:level="2"><nlm:aff id="A64">Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A65">Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Halfpenny, Christopher" sort="Halfpenny, Christopher" uniqKey="Halfpenny C" first="Christopher" last="Halfpenny">Christopher Halfpenny</name><affiliation wicri:level="1"><nlm:aff id="A66">Wellcome Trust Clinical Research Facility, Southampton General Hospital, Southampton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Clinical Research Facility, Southampton General Hospital, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation></author><author><name sortKey="Hall, Gillian" sort="Hall, Gillian" uniqKey="Hall G" first="Gillian" last="Hall">Gillian Hall</name><affiliation wicri:level="1"><nlm:aff id="A67">Department of Neurology, Aberdeen Royal Infirmary, Aberdeen, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Aberdeen Royal Infirmary, Aberdeen</wicri:regionArea><wicri:noRegion>Aberdeen</wicri:noRegion></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation wicri:level="3"><nlm:aff id="A68">Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name><affiliation wicri:level="3"><nlm:aff id="A69">Department of Medicine at Karolinska University Hospital Solna, Atherosclerosis Research Unit, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medicine at Karolinska University Hospital Solna, Atherosclerosis Research Unit, Center for Molecular Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Harley, James" sort="Harley, James" uniqKey="Harley J" first="James" last="Harley">James Harley</name><affiliation wicri:level="1"><nlm:aff id="A70">Department of Neurology, Hull Royal Infirmary, Hull, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Hull Royal Infirmary, Hull</wicri:regionArea><wicri:noRegion>Hull</wicri:noRegion></affiliation></author><author><name sortKey="Harrower, Timothy" sort="Harrower, Timothy" uniqKey="Harrower T" first="Timothy" last="Harrower">Timothy Harrower</name><affiliation wicri:level="1"><nlm:aff id="A71">Department of Neurology, Royal Devon and Exeter Foundaton Trust Hospital, Exeter, Devon, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Royal Devon and Exeter Foundaton Trust Hospital, Exeter, Devon</wicri:regionArea><wicri:noRegion>Devon</wicri:noRegion></affiliation></author><author><name sortKey="Hawkins, Clive" sort="Hawkins, Clive" uniqKey="Hawkins C" first="Clive" last="Hawkins">Clive Hawkins</name><affiliation wicri:level="1"><nlm:aff id="A72">Keele University Medical School, University Hospital of North Staffordshire, Stoke-on-Trent, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Keele University Medical School, University Hospital of North Staffordshire, Stoke-on-Trent</wicri:regionArea><wicri:noRegion>Stoke-on-Trent</wicri:noRegion></affiliation></author><author><name sortKey="Hellenthal, Garrett" sort="Hellenthal, Garrett" uniqKey="Hellenthal G" first="Garrett" last="Hellenthal">Garrett Hellenthal</name><affiliation wicri:level="4"><nlm:aff id="A73">UCL Genetics Institute (UGI), University College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>UCL Genetics Institute (UGI), University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Hillier, Charles" sort="Hillier, Charles" uniqKey="Hillier C" first="Charles" last="Hillier">Charles Hillier</name><affiliation wicri:level="1"><nlm:aff id="A74">Department of Neurology, Poole General Hospital, Poole, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Poole General Hospital, Poole</wicri:regionArea><wicri:noRegion>Poole</wicri:noRegion></affiliation></author><author><name sortKey="Hobart, Jeremy" sort="Hobart, Jeremy" uniqKey="Hobart J" first="Jeremy" last="Hobart">Jeremy Hobart</name><affiliation wicri:level="1"><nlm:aff id="A75">Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth</wicri:regionArea><wicri:noRegion>Plymouth</wicri:noRegion></affiliation></author><author><name sortKey="Hoshi, Muni" sort="Hoshi, Muni" uniqKey="Hoshi M" first="Muni" last="Hoshi">Muni Hoshi</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Hunt, Sarah E" sort="Hunt, Sarah E" uniqKey="Hunt S" first="Sarah E" last="Hunt">Sarah E. Hunt</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Jagodic, Maja" sort="Jagodic, Maja" uniqKey="Jagodic M" first="Maja" last="Jagodic">Maja Jagodic</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Jel I, Ilijas" sort="Jel I, Ilijas" uniqKey="Jel I I" first="Ilijas" last="Jel I">Ilijas Jel I</name><affiliation wicri:level="3"><nlm:aff id="A76">Institute for Neuroimmunology and Clinical MS Research (inims), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Neuroimmunology and Clinical MS Research (inims), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A77">Department of Neuroimmunology and MS Research, Neurology Clinic, University Hospital Zürich, Zürich, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Neuroimmunology and MS Research, Neurology Clinic, University Hospital Zürich, Zürich</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName></affiliation></author><author><name sortKey="Jochim, Angela" sort="Jochim, Angela" uniqKey="Jochim A" first="Angela" last="Jochim">Angela Jochim</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Kendall, Brian" sort="Kendall, Brian" uniqKey="Kendall B" first="Brian" last="Kendall">Brian Kendall</name><affiliation wicri:level="1"><nlm:aff id="A78">Department of Neurology, Division of Clinical Neurology, Leicester Royal Infirmary, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Division of Clinical Neurology, Leicester Royal Infirmary, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation></author><author><name sortKey="Kermode, Allan" sort="Kermode, Allan" uniqKey="Kermode A" first="Allan" last="Kermode">Allan Kermode</name><affiliation wicri:level="1"><nlm:aff id="A79">Australian Neuromuscular Research Institute, University of Western Australia, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Australian Neuromuscular Research Institute, University of Western Australia, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A80">Murdoch University, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Murdoch University, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Kilpatrick, Trevor" sort="Kilpatrick, Trevor" uniqKey="Kilpatrick T" first="Trevor" last="Kilpatrick">Trevor Kilpatrick</name><affiliation wicri:level="4"><nlm:aff id="A81">Melbourne Neuroscience Institute, University of Melbourne, Victoria, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Melbourne Neuroscience Institute, University of Melbourne, Victoria</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Koivisto, Keijo" sort="Koivisto, Keijo" uniqKey="Koivisto K" first="Keijo" last="Koivisto">Keijo Koivisto</name><affiliation wicri:level="1"><nlm:aff id="A82">Department of Neurology, Seinäjoki Central Hospital, Seinäjoki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Neurology, Seinäjoki Central Hospital, Seinäjoki</wicri:regionArea><wicri:noRegion>Seinäjoki</wicri:noRegion></affiliation></author><author><name sortKey="Konidari, Ioanna" sort="Konidari, Ioanna" uniqKey="Konidari I" first="Ioanna" last="Konidari">Ioanna Konidari</name><affiliation wicri:level="2"><nlm:aff id="A1">John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Korn, Thomas" sort="Korn, Thomas" uniqKey="Korn T" first="Thomas" last="Korn">Thomas Korn</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Kronsbein, Helena" sort="Kronsbein, Helena" uniqKey="Kronsbein H" first="Helena" last="Kronsbein">Helena Kronsbein</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Langford, Cordelia" sort="Langford, Cordelia" uniqKey="Langford C" first="Cordelia" last="Langford">Cordelia Langford</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Larsson, Malin" sort="Larsson, Malin" uniqKey="Larsson M" first="Malin" last="Larsson">Malin Larsson</name><affiliation wicri:level="1"><nlm:aff id="A83">IFM Bioinformatics, Linköping University, Linköping, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>IFM Bioinformatics, Linköping University, Linköping</wicri:regionArea><wicri:noRegion>Linköping</wicri:noRegion></affiliation></author><author><name sortKey="Lathrop, Mark" sort="Lathrop, Mark" uniqKey="Lathrop M" first="Mark" last="Lathrop">Mark Lathrop</name><affiliation wicri:level="3"><nlm:aff id="A84">Fondation Jean Dausset - Centre d’Etude du Polymorphisme Humain, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Fondation Jean Dausset - Centre d’Etude du Polymorphisme Humain, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A85">Commissariat à l’Energie Atomique, Institut Genomique, Centre National de Génotypage, Evry, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Commissariat à l’Energie Atomique, Institut Genomique, Centre National de Génotypage, Evry</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Évry (Essonne)</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A86">McGill University and Genome Quebec Innovation Center, Montreal, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>McGill University and Genome Quebec Innovation Center, Montreal</wicri:regionArea><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Lebrun Frenay, Christine" sort="Lebrun Frenay, Christine" uniqKey="Lebrun Frenay C" first="Christine" last="Lebrun-Frenay">Christine Lebrun-Frenay</name><affiliation wicri:level="1"><nlm:aff id="A87">Service de Neurologie, Hôpital Pasteur, CHRU Nice, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, Hôpital Pasteur, CHRU Nice</wicri:regionArea><wicri:noRegion>CHRU Nice</wicri:noRegion><wicri:noRegion>CHRU Nice</wicri:noRegion></affiliation></author><author><name sortKey="Lechner Scott, Jeannette" sort="Lechner Scott, Jeannette" uniqKey="Lechner Scott J" first="Jeannette" last="Lechner-Scott">Jeannette Lechner-Scott</name><affiliation wicri:level="1"><nlm:aff id="A88">Hunter Medical Research Institute, University of Newcastle, New South Wales, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Hunter Medical Research Institute, University of Newcastle, New South Wales</wicri:regionArea><wicri:noRegion>New South Wales</wicri:noRegion></affiliation></author><author><name sortKey="Lee, Michelle H" sort="Lee, Michelle H" uniqKey="Lee M" first="Michelle H" last="Lee">Michelle H. Lee</name><affiliation wicri:level="2"><nlm:aff id="A2">Department of Neurology, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Brigham & Women’s Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Brigham & Women’s Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Leone, Maurizio A" sort="Leone, Maurizio A" uniqKey="Leone M" first="Maurizio A" last="Leone">Maurizio A. Leone</name><affiliation wicri:level="1"><nlm:aff id="A89">Department of Neurology, Ospedale Maggiore, Novara, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Ospedale Maggiore, Novara</wicri:regionArea><wicri:noRegion>Novara</wicri:noRegion></affiliation></author><author><name sortKey="Lepp, Virpi" sort="Lepp, Virpi" uniqKey="Lepp V" first="Virpi" last="Lepp">Virpi Lepp</name><affiliation wicri:level="4"><nlm:aff id="A17">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Liberatore, Giuseppe" sort="Liberatore, Giuseppe" uniqKey="Liberatore G" first="Giuseppe" last="Liberatore">Giuseppe Liberatore</name><affiliation wicri:level="3"><nlm:aff id="A25">Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A26">Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Lie, Benedicte A" sort="Lie, Benedicte A" uniqKey="Lie B" first="Benedicte A" last="Lie">Benedicte A. Lie</name><affiliation wicri:level="3"><nlm:aff id="A29">University of Oslo, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A90">Department of Medical Genetics, Oslo University Hospital, Ullevål, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Medical Genetics, Oslo University Hospital, Ullevål, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Lill, Christina M" sort="Lill, Christina M" uniqKey="Lill C" first="Christina M" last="Lill">Christina M. Lill</name><affiliation wicri:level="3"><nlm:aff id="A23">Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz</wicri:regionArea><placeName><region type="land" nuts="2">Rhénanie-Palatinat</region><settlement type="city">Mayence</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A91">Department of Vertebrate Genomics, Neuropsychiatric Genetics Group, Max Planck Institute for Molecular Genetics, Berlin, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Vertebrate Genomics, Neuropsychiatric Genetics Group, Max Planck Institute for Molecular Genetics, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Linden, Magdalena" sort="Linden, Magdalena" uniqKey="Linden M" first="Magdalena" last="Lindén">Magdalena Lindén</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Link, Jenny" sort="Link, Jenny" uniqKey="Link J" first="Jenny" last="Link">Jenny Link</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Luessi, Felix" sort="Luessi, Felix" uniqKey="Luessi F" first="Felix" last="Luessi">Felix Luessi</name><affiliation wicri:level="3"><nlm:aff id="A23">Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz</wicri:regionArea><placeName><region type="land" nuts="2">Rhénanie-Palatinat</region><settlement type="city">Mayence</settlement></placeName></affiliation></author><author><name sortKey="Lycke, Jan" sort="Lycke, Jan" uniqKey="Lycke J" first="Jan" last="Lycke">Jan Lycke</name><affiliation wicri:level="1"><nlm:aff id="A92">Department of Clinical Neurosciences and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Göteborgs Universitet, Göteborg, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neurosciences and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Göteborgs Universitet, Göteborg</wicri:regionArea><wicri:noRegion>Göteborg</wicri:noRegion></affiliation></author><author><name sortKey="Macciardi, Fabio" sort="Macciardi, Fabio" uniqKey="Macciardi F" first="Fabio" last="Macciardi">Fabio Macciardi</name><affiliation wicri:level="2"><nlm:aff id="A93">Department of Psychiatry and Human Behavior, School of Medicine, University of California, Irvine, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry and Human Behavior, School of Medicine, University of California, Irvine, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A94">Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="M Nnisto, Satu" sort="M Nnisto, Satu" uniqKey="M Nnisto S" first="Satu" last="M Nnistö">Satu M Nnistö</name><affiliation wicri:level="1"><nlm:aff id="A95">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Manrique, Clara P" sort="Manrique, Clara P" uniqKey="Manrique C" first="Clara P" last="Manrique">Clara P. Manrique</name><affiliation wicri:level="2"><nlm:aff id="A1">John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Martin, Roland" sort="Martin, Roland" uniqKey="Martin R" first="Roland" last="Martin">Roland Martin</name><affiliation wicri:level="3"><nlm:aff id="A76">Institute for Neuroimmunology and Clinical MS Research (inims), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Neuroimmunology and Clinical MS Research (inims), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A77">Department of Neuroimmunology and MS Research, Neurology Clinic, University Hospital Zürich, Zürich, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Neuroimmunology and MS Research, Neurology Clinic, University Hospital Zürich, Zürich</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName></affiliation></author><author><name sortKey="Martinelli, Vittorio" sort="Martinelli, Vittorio" uniqKey="Martinelli V" first="Vittorio" last="Martinelli">Vittorio Martinelli</name><affiliation wicri:level="3"><nlm:aff id="A26">Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Mason, Deborah" sort="Mason, Deborah" uniqKey="Mason D" first="Deborah" last="Mason">Deborah Mason</name><affiliation wicri:level="1"><nlm:aff id="A96">Canterbury District Health Board, Christchurch, New Zealand</nlm:aff><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Canterbury District Health Board, Christchurch</wicri:regionArea><wicri:noRegion>Christchurch</wicri:noRegion></affiliation></author><author><name sortKey="Mazibrada, Gordon" sort="Mazibrada, Gordon" uniqKey="Mazibrada G" first="Gordon" last="Mazibrada">Gordon Mazibrada</name><affiliation wicri:level="3"><nlm:aff id="A97">Department of Neurology, Queen Elizabeth Medical Centre, Edgbaston, Birmingham, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Queen Elizabeth Medical Centre, Edgbaston, Birmingham</wicri:regionArea><placeName><settlement type="city">Birmingham</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Midlands de l'Ouest</region></placeName></affiliation></author><author><name sortKey="Mccabe, Cristin" sort="Mccabe, Cristin" uniqKey="Mccabe C" first="Cristin" last="Mccabe">Cristin Mccabe</name><affiliation wicri:level="2"><nlm:aff id="A10">Program in Medical and Population Genetics, Broad Institute of Harvard University and MIT, Cambridge, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard University and MIT, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Mero, Inger Lise" sort="Mero, Inger Lise" uniqKey="Mero I" first="Inger-Lise" last="Mero">Inger-Lise Mero</name><affiliation wicri:level="3"><nlm:aff id="A28">Department of Neurology, Oslo University Hospital, Ullevål, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Neurology, Oslo University Hospital, Ullevål, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A29">University of Oslo, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A90">Department of Medical Genetics, Oslo University Hospital, Ullevål, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Medical Genetics, Oslo University Hospital, Ullevål, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Mescheriakova, Julia" sort="Mescheriakova, Julia" uniqKey="Mescheriakova J" first="Julia" last="Mescheriakova">Julia Mescheriakova</name><affiliation wicri:level="3"><nlm:aff id="A32">Department of Neurology, MS Center ErasMS, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, MS Center ErasMS, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Moutsianas, Loukas" sort="Moutsianas, Loukas" uniqKey="Moutsianas L" first="Loukas" last="Moutsianas">Loukas Moutsianas</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Myhr, Kjell Morten" sort="Myhr, Kjell Morten" uniqKey="Myhr K" first="Kjell-Morten" last="Myhr">Kjell-Morten Myhr</name><affiliation wicri:level="1"><nlm:aff id="A98">Department of Neurology, The Norwegian Multiple Sclerosis Registry and Biobank, Haukeland University Hospital, Bergen, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Neurology, The Norwegian Multiple Sclerosis Registry and Biobank, Haukeland University Hospital, Bergen</wicri:regionArea><wicri:noRegion>Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Nagels, Guy" sort="Nagels, Guy" uniqKey="Nagels G" first="Guy" last="Nagels">Guy Nagels</name><affiliation wicri:level="1"><nlm:aff id="A99">National Multiple Sclerosis Center Melsbroek, Melsbroek, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>National Multiple Sclerosis Center Melsbroek, Melsbroek</wicri:regionArea><wicri:noRegion>Melsbroek</wicri:noRegion></affiliation></author><author><name sortKey="Nicholas, Richard" sort="Nicholas, Richard" uniqKey="Nicholas R" first="Richard" last="Nicholas">Richard Nicholas</name><affiliation wicri:level="3"><nlm:aff id="A100">Neurology Department, Charing Cross Hospital, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Neurology Department, Charing Cross Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Nilsson, Petra" sort="Nilsson, Petra" uniqKey="Nilsson P" first="Petra" last="Nilsson">Petra Nilsson</name><affiliation wicri:level="1"><nlm:aff id="A101">Department of Clinical Sciences, Lund University, Lund, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Sciences, Lund University, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name sortKey="Piehl, Fredrik" sort="Piehl, Fredrik" uniqKey="Piehl F" first="Fredrik" last="Piehl">Fredrik Piehl</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Pirinen, Matti" sort="Pirinen, Matti" uniqKey="Pirinen M" first="Matti" last="Pirinen">Matti Pirinen</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Price, Sian E" sort="Price, Sian E" uniqKey="Price S" first="Siân E" last="Price">Siân E. Price</name><affiliation wicri:level="1"><nlm:aff id="A102">Department of Neurology, Royal Hallamshire Hospital, Sheffield, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Royal Hallamshire Hospital, Sheffield</wicri:regionArea><wicri:noRegion>Sheffield</wicri:noRegion></affiliation></author><author><name sortKey="Quach, Hong" sort="Quach, Hong" uniqKey="Quach H" first="Hong" last="Quach">Hong Quach</name><affiliation wicri:level="2"><nlm:aff id="A33">Division of Epidemiology, Genetic Epidemiology and Genomics Laboratory, School of Public Health, University of California, Berkeley, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology, Genetic Epidemiology and Genomics Laboratory, School of Public Health, University of California, Berkeley, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Reunanen, Mauri" sort="Reunanen, Mauri" uniqKey="Reunanen M" first="Mauri" last="Reunanen">Mauri Reunanen</name><affiliation wicri:level="1"><nlm:aff id="A103">Department of Neurology, University of Oulu, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Neurology, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A104">Department of Neurology, University Hospital of Oulu, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Neurology, University Hospital of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Robberecht, Wim" sort="Robberecht, Wim" uniqKey="Robberecht W" first="Wim" last="Robberecht">Wim Robberecht</name><affiliation wicri:level="1"><nlm:aff id="A105">Laboratory of Neurobiology, Vesalius Research Center, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Laboratory of Neurobiology, Vesalius Research Center, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A106">Experimental Neurology, Leuven Research Institute for Neurodegenerative Diseases (LIND), University of Leuven (KU Leuven), Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Experimental Neurology, Leuven Research Institute for Neurodegenerative Diseases (LIND), University of Leuven (KU Leuven), Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A107">Department of Neurology, University Hospitals Leuven, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Neurology, University Hospitals Leuven, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Robertson, Neil P" sort="Robertson, Neil P" uniqKey="Robertson N" first="Neil P" last="Robertson">Neil P. Robertson</name><affiliation wicri:level="1"><nlm:aff id="A108">Institute of Psychological Medicine and Clinical Neuroscience, Cardiff University, University Hospital of Wales, Cardiff, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neuroscience, Cardiff University, University Hospital of Wales, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Rodegher, Mariaemma" sort="Rodegher, Mariaemma" uniqKey="Rodegher M" first="Mariaemma" last="Rodegher">Mariaemma Rodegher</name><affiliation wicri:level="3"><nlm:aff id="A26">Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Rog, David" sort="Rog, David" uniqKey="Rog D" first="David" last="Rog">David Rog</name><affiliation wicri:level="1"><nlm:aff id="A109">Department of Neurology, Greater Manchester Neurosciences Centre, Salford Royal NHS Foundation Trust, Salford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Greater Manchester Neurosciences Centre, Salford Royal NHS Foundation Trust, Salford</wicri:regionArea><wicri:noRegion>Salford</wicri:noRegion></affiliation></author><author><name sortKey="Salvetti, Marco" sort="Salvetti, Marco" uniqKey="Salvetti M" first="Marco" last="Salvetti">Marco Salvetti</name><affiliation wicri:level="3"><nlm:aff id="A110">Department of Neuroscience, Centre for Experimental Neurological Therapies, Mental Health and Sensory Organs, Sapienza Università di Roma, Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neuroscience, Centre for Experimental Neurological Therapies, Mental Health and Sensory Organs, Sapienza Università di Roma, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Schnetz Boutaud, Nathalie C" sort="Schnetz Boutaud, Nathalie C" uniqKey="Schnetz Boutaud N" first="Nathalie C" last="Schnetz-Boutaud">Nathalie C. Schnetz-Boutaud</name><affiliation wicri:level="2"><nlm:aff id="A8">Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Sellebjerg, Finn" sort="Sellebjerg, Finn" uniqKey="Sellebjerg F" first="Finn" last="Sellebjerg">Finn Sellebjerg</name><affiliation wicri:level="3"><nlm:aff id="A16">Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Selter, Rebecca C" sort="Selter, Rebecca C" uniqKey="Selter R" first="Rebecca C" last="Selter">Rebecca C. Selter</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Schaefer, Catherine" sort="Schaefer, Catherine" uniqKey="Schaefer C" first="Catherine" last="Schaefer">Catherine Schaefer</name><affiliation wicri:level="2"><nlm:aff id="A35">Kaiser Permanente Division of Research, Oakland, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Kaiser Permanente Division of Research, Oakland, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Shaunak, Sandip" sort="Shaunak, Sandip" uniqKey="Shaunak S" first="Sandip" last="Shaunak">Sandip Shaunak</name><affiliation wicri:level="1"><nlm:aff id="A111">Department of Neurology, Royal Preston Hospital, Preston, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Royal Preston Hospital, Preston</wicri:regionArea><wicri:noRegion>Preston</wicri:noRegion></affiliation></author><author><name sortKey="Shen, Ling" sort="Shen, Ling" uniqKey="Shen L" first="Ling" last="Shen">Ling Shen</name><affiliation wicri:level="2"><nlm:aff id="A35">Kaiser Permanente Division of Research, Oakland, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Kaiser Permanente Division of Research, Oakland, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Shields, Simon" sort="Shields, Simon" uniqKey="Shields S" first="Simon" last="Shields">Simon Shields</name><affiliation wicri:level="1"><nlm:aff id="A112">Department of Neurology, Norfolk and Norwich Hospital, Norwich, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Norfolk and Norwich Hospital, Norwich</wicri:regionArea><wicri:noRegion>Norwich</wicri:noRegion></affiliation></author><author><name sortKey="Siffrin, Volker" sort="Siffrin, Volker" uniqKey="Siffrin V" first="Volker" last="Siffrin">Volker Siffrin</name><affiliation wicri:level="3"><nlm:aff id="A23">Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz</wicri:regionArea><placeName><region type="land" nuts="2">Rhénanie-Palatinat</region><settlement type="city">Mayence</settlement></placeName></affiliation></author><author><name sortKey="Slee, Mark" sort="Slee, Mark" uniqKey="Slee M" first="Mark" last="Slee">Mark Slee</name><affiliation wicri:level="1"><nlm:aff id="A113">Department of Neurology, Flinders University, Adelaide, South Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Neurology, Flinders University, Adelaide, South Australia</wicri:regionArea><wicri:noRegion>South Australia</wicri:noRegion></affiliation></author><author><name sortKey="Sorensen, Per Soelberg" sort="Sorensen, Per Soelberg" uniqKey="Sorensen P" first="Per Soelberg" last="Sorensen">Per Soelberg Sorensen</name><affiliation wicri:level="3"><nlm:aff id="A16">Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Sorosina, Melissa" sort="Sorosina, Melissa" uniqKey="Sorosina M" first="Melissa" last="Sorosina">Melissa Sorosina</name><affiliation wicri:level="3"><nlm:aff id="A25">Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Sospedra, Mireia" sort="Sospedra, Mireia" uniqKey="Sospedra M" first="Mireia" last="Sospedra">Mireia Sospedra</name><affiliation wicri:level="3"><nlm:aff id="A76">Institute for Neuroimmunology and Clinical MS Research (inims), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Neuroimmunology and Clinical MS Research (inims), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A77">Department of Neuroimmunology and MS Research, Neurology Clinic, University Hospital Zürich, Zürich, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Neuroimmunology and MS Research, Neurology Clinic, University Hospital Zürich, Zürich</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName></affiliation></author><author><name sortKey="Spurkland, Anne" sort="Spurkland, Anne" uniqKey="Spurkland A" first="Anne" last="Spurkland">Anne Spurkland</name><affiliation wicri:level="3"><nlm:aff id="A114">Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Institute of Basic Medical Sciences, University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Strange, Amy" sort="Strange, Amy" uniqKey="Strange A" first="Amy" last="Strange">Amy Strange</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Sundqvist, Emilie" sort="Sundqvist, Emilie" uniqKey="Sundqvist E" first="Emilie" last="Sundqvist">Emilie Sundqvist</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Thijs, Vincent" sort="Thijs, Vincent" uniqKey="Thijs V" first="Vincent" last="Thijs">Vincent Thijs</name><affiliation wicri:level="1"><nlm:aff id="A105">Laboratory of Neurobiology, Vesalius Research Center, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Laboratory of Neurobiology, Vesalius Research Center, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A106">Experimental Neurology, Leuven Research Institute for Neurodegenerative Diseases (LIND), University of Leuven (KU Leuven), Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Experimental Neurology, Leuven Research Institute for Neurodegenerative Diseases (LIND), University of Leuven (KU Leuven), Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A107">Department of Neurology, University Hospitals Leuven, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Neurology, University Hospitals Leuven, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Thorpe, John" sort="Thorpe, John" uniqKey="Thorpe J" first="John" last="Thorpe">John Thorpe</name><affiliation wicri:level="1"><nlm:aff id="A115">Department of Neurology, Peterborough City Hospital, Peterborough, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Peterborough City Hospital, Peterborough</wicri:regionArea><wicri:noRegion>Peterborough</wicri:noRegion></affiliation></author><author><name sortKey="Ticca, Anna" sort="Ticca, Anna" uniqKey="Ticca A" first="Anna" last="Ticca">Anna Ticca</name><affiliation wicri:level="1"><nlm:aff id="A116">Neurology and Stroke Unit, San Francesco Hospital, Nuoro, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Neurology and Stroke Unit, San Francesco Hospital, Nuoro</wicri:regionArea><wicri:noRegion>Nuoro</wicri:noRegion></affiliation></author><author><name sortKey="Tienari, Pentti" sort="Tienari, Pentti" uniqKey="Tienari P" first="Pentti" last="Tienari">Pentti Tienari</name><affiliation wicri:level="1"><nlm:aff id="A117">Department of Neurology, Helsinki University Central Hospital and Molecular Neurology Programme, Biomedicum, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Neurology, Helsinki University Central Hospital and Molecular Neurology Programme, Biomedicum, University of Helsinki, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Van Duijn, Cornelia" sort="Van Duijn, Cornelia" uniqKey="Van Duijn C" first="Cornelia" last="Van Duijn">Cornelia Van Duijn</name><affiliation wicri:level="3"><nlm:aff id="A118">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Visser, Elizabeth M" sort="Visser, Elizabeth M" uniqKey="Visser E" first="Elizabeth M" last="Visser">Elizabeth M. Visser</name><affiliation wicri:level="1"><nlm:aff id="A119">Division of Applied Health Sciences, University of Aberdeen, Foresterhill, Aberdeen, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Applied Health Sciences, University of Aberdeen, Foresterhill, Aberdeen</wicri:regionArea><wicri:noRegion>Aberdeen</wicri:noRegion></affiliation></author><author><name sortKey="Vucic, Steve" sort="Vucic, Steve" uniqKey="Vucic S" first="Steve" last="Vucic">Steve Vucic</name><affiliation wicri:level="4"><nlm:aff id="A14">Westmead Millennium Institute, University of Sydney, New South Wales, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Westmead Millennium Institute, University of Sydney, New South Wales</wicri:regionArea><orgName type="university">Université de Sydney</orgName><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Westerlind, Helga" sort="Westerlind, Helga" uniqKey="Westerlind H" first="Helga" last="Westerlind">Helga Westerlind</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Wiley, James S" sort="Wiley, James S" uniqKey="Wiley J" first="James S" last="Wiley">James S. Wiley</name><affiliation wicri:level="4"><nlm:aff id="A58">Florey Institute of Neuroscience and Mental Health, University of Melbourne, Victoria, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Florey Institute of Neuroscience and Mental Health, University of Melbourne, Victoria</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Wilkins, Alastair" sort="Wilkins, Alastair" uniqKey="Wilkins A" first="Alastair" last="Wilkins">Alastair Wilkins</name><affiliation wicri:level="1"><nlm:aff id="A120">Institute of Clinical Neurosciences, University of Bristol, Frenchay Hospital, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Clinical Neurosciences, University of Bristol, Frenchay Hospital, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><affiliation wicri:level="4"><nlm:aff id="A121">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Winkelmann, Juliane" sort="Winkelmann, Juliane" uniqKey="Winkelmann J" first="Juliane" last="Winkelmann">Juliane Winkelmann</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A20">Munich Cluster for Systems Neurology (SyNergy), Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Munich Cluster for Systems Neurology (SyNergy), Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A122">Institut für Humangenetik, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Humangenetik, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A123">Institut für Humangenetik, Helmholtz Zentrum München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Humangenetik, Helmholtz Zentrum München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Zajicek, John" sort="Zajicek, John" uniqKey="Zajicek J" first="John" last="Zajicek">John Zajicek</name><affiliation wicri:level="1"><nlm:aff id="A75">Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth</wicri:regionArea><wicri:noRegion>Plymouth</wicri:noRegion></affiliation></author><author><name sortKey="Zindler, Eva" sort="Zindler, Eva" uniqKey="Zindler E" first="Eva" last="Zindler">Eva Zindler</name><affiliation wicri:level="3"><nlm:aff id="A23">Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz</wicri:regionArea><placeName><region type="land" nuts="2">Rhénanie-Palatinat</region><settlement type="city">Mayence</settlement></placeName></affiliation></author><author><name sortKey="Haines, Jonathan L" sort="Haines, Jonathan L" uniqKey="Haines J" first="Jonathan L" last="Haines">Jonathan L. Haines</name><affiliation wicri:level="2"><nlm:aff id="A8">Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Pericak Vance, Margaret A" sort="Pericak Vance, Margaret A" uniqKey="Pericak Vance M" first="Margaret A" last="Pericak-Vance">Margaret A. Pericak-Vance</name><affiliation wicri:level="2"><nlm:aff id="A1">John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Ivinson, Adrian J" sort="Ivinson, Adrian J" uniqKey="Ivinson A" first="Adrian J" last="Ivinson">Adrian J. Ivinson</name><affiliation wicri:level="2"><nlm:aff id="A124">Harvard NeuroDiscovery Center, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard NeuroDiscovery Center, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Stewart, Graeme" sort="Stewart, Graeme" uniqKey="Stewart G" first="Graeme" last="Stewart">Graeme Stewart</name><affiliation wicri:level="4"><nlm:aff id="A14">Westmead Millennium Institute, University of Sydney, New South Wales, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Westmead Millennium Institute, University of Sydney, New South Wales</wicri:regionArea><orgName type="university">Université de Sydney</orgName><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Hafler, David" sort="Hafler, David" uniqKey="Hafler D" first="David" last="Hafler">David Hafler</name><affiliation wicri:level="2"><nlm:aff id="A10">Program in Medical and Population Genetics, Broad Institute of Harvard University and MIT, Cambridge, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard University and MIT, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A11">Department of Neurology, Yale University School of Medicine, New Haven, Connecticut, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Yale University School of Medicine, New Haven, Connecticut</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A125">Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation></author><author><name sortKey="Hauser, Stephen L" sort="Hauser, Stephen L" uniqKey="Hauser S" first="Stephen L" last="Hauser">Stephen L. Hauser</name><affiliation wicri:level="2"><nlm:aff id="A31">Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Compston, Alastair" sort="Compston, Alastair" uniqKey="Compston A" first="Alastair" last="Compston">Alastair Compston</name><affiliation wicri:level="4"><nlm:aff id="A9">Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Mcvean, Gil" sort="Mcvean, Gil" uniqKey="Mcvean G" first="Gil" last="Mcvean">Gil Mcvean</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="De Jager, Philip" sort="De Jager, Philip" uniqKey="De Jager P" first="Philip" last="De Jager">Philip De Jager</name><affiliation wicri:level="2"><nlm:aff id="A2">Department of Neurology, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Brigham & Women’s Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Brigham & Women’s Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A5">Harvard Medical School, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A10">Program in Medical and Population Genetics, Broad Institute of Harvard University and MIT, Cambridge, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard University and MIT, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Sawcer, Stephen" sort="Sawcer, Stephen" uniqKey="Sawcer S" first="Stephen" last="Sawcer">Stephen Sawcer</name><affiliation wicri:level="4"><nlm:aff id="A9">Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Mccauley, Jacob L" sort="Mccauley, Jacob L" uniqKey="Mccauley J" first="Jacob L" last="Mccauley">Jacob L. Mccauley</name><affiliation wicri:level="2"><nlm:aff id="A1">John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24076602</idno><idno type="pmc">3832895</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832895</idno><idno type="RBID">PMC:3832895</idno><idno type="doi">10.1038/ng.2770</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">002E29</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002E29</idno><idno type="wicri:Area/Pmc/Curation">002C79</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002C79</idno><idno type="wicri:Area/Pmc/Checkpoint">001C58</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001C58</idno><idno type="wicri:Area/Ncbi/Merge">001489</idno><idno type="wicri:Area/Ncbi/Curation">001489</idno><idno type="wicri:Area/Ncbi/Checkpoint">001489</idno><idno type="wicri:doubleKey">1061-4036:2013:Beecham A:analysis:of:immune</idno><idno type="wicri:Area/Main/Merge">004962</idno><idno type="wicri:Area/Main/Curation">004842</idno><idno type="wicri:Area/Main/Exploration">004842</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis</title><author><name sortKey="Beecham, Ashley H" sort="Beecham, Ashley H" uniqKey="Beecham A" first="Ashley H" last="Beecham">Ashley H. Beecham</name><affiliation wicri:level="2"><nlm:aff id="A1">John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Patsopoulos, Nikolaos A" sort="Patsopoulos, Nikolaos A" uniqKey="Patsopoulos N" first="Nikolaos A" last="Patsopoulos">Nikolaos A. Patsopoulos</name><affiliation wicri:level="2"><nlm:aff id="A2">Department of Neurology, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Brigham & Women’s Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Brigham & Women’s Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A3">Department of Psychiatry, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Brigham & Women’s Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Brigham & Women’s Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A4">Department of Medicine, Division of Genetics, Brigham & Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Division of Genetics, Brigham & Women’s Hospital, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A5">Harvard Medical School, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A6">Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Xifara, Dionysia K" sort="Xifara, Dionysia K" uniqKey="Xifara D" first="Dionysia K" last="Xifara">Dionysia K. Xifara</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Davis, Mary F" sort="Davis, Mary F" uniqKey="Davis M" first="Mary F" last="Davis">Mary F. Davis</name><affiliation wicri:level="2"><nlm:aff id="A8">Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Kemppinen, Anu" sort="Kemppinen, Anu" uniqKey="Kemppinen A" first="Anu" last="Kemppinen">Anu Kemppinen</name><affiliation wicri:level="4"><nlm:aff id="A9">Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Cotsapas, Chris" sort="Cotsapas, Chris" uniqKey="Cotsapas C" first="Chris" last="Cotsapas">Chris Cotsapas</name><affiliation wicri:level="2"><nlm:aff id="A10">Program in Medical and Population Genetics, Broad Institute of Harvard University and MIT, Cambridge, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard University and MIT, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A11">Department of Neurology, Yale University School of Medicine, New Haven, Connecticut, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Yale University School of Medicine, New Haven, Connecticut</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A12">Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Yale University School of Medicine, New Haven, Connecticut</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation></author><author><name sortKey="Shahi, Tejas S" sort="Shahi, Tejas S" uniqKey="Shahi T" first="Tejas S" last="Shahi">Tejas S. Shahi</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Spencer, Chris" sort="Spencer, Chris" uniqKey="Spencer C" first="Chris" last="Spencer">Chris Spencer</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Booth, David" sort="Booth, David" uniqKey="Booth D" first="David" last="Booth">David Booth</name><affiliation wicri:level="4"><nlm:aff id="A14">Westmead Millennium Institute, University of Sydney, New South Wales, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Westmead Millennium Institute, University of Sydney, New South Wales</wicri:regionArea><orgName type="university">Université de Sydney</orgName><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Goris, An" sort="Goris, An" uniqKey="Goris A" first="An" last="Goris">An Goris</name><affiliation wicri:level="1"><nlm:aff id="A15">Section of Experimental Neurology, Laboratory for Neuroimmunology, KU Leuven, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Section of Experimental Neurology, Laboratory for Neuroimmunology, KU Leuven, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Oturai, Annette" sort="Oturai, Annette" uniqKey="Oturai A" first="Annette" last="Oturai">Annette Oturai</name><affiliation wicri:level="3"><nlm:aff id="A16">Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Saarela, Janna" sort="Saarela, Janna" uniqKey="Saarela J" first="Janna" last="Saarela">Janna Saarela</name><affiliation wicri:level="4"><nlm:aff id="A17">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Fontaine, Bertrand" sort="Fontaine, Bertrand" uniqKey="Fontaine B" first="Bertrand" last="Fontaine">Bertrand Fontaine</name><affiliation wicri:level="3"><nlm:aff id="A18">Département de Neurologie, INSERM UMR S 975 CRICM, UPMC, Pitié-Salpêtrière, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Département de Neurologie, INSERM UMR S 975 CRICM, UPMC, Pitié-Salpêtrière, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Hemmer, Bernhard" sort="Hemmer, Bernhard" uniqKey="Hemmer B" first="Bernhard" last="Hemmer">Bernhard Hemmer</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A20">Munich Cluster for Systems Neurology (SyNergy), Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Munich Cluster for Systems Neurology (SyNergy), Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A21">German Competence Network Multiple Sclerosis (KKNMS), Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Competence Network Multiple Sclerosis (KKNMS), Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Martin, Claes" sort="Martin, Claes" uniqKey="Martin C" first="Claes" last="Martin">Claes Martin</name><affiliation wicri:level="3"><nlm:aff id="A22">Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Zipp, Frauke" sort="Zipp, Frauke" uniqKey="Zipp F" first="Frauke" last="Zipp">Frauke Zipp</name><affiliation wicri:level="3"><nlm:aff id="A23">Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz</wicri:regionArea><placeName><region type="land" nuts="2">Rhénanie-Palatinat</region><settlement type="city">Mayence</settlement></placeName></affiliation></author><author><name sortKey="D Lfonso, Sandra" sort="D Lfonso, Sandra" uniqKey="D Lfonso S" first="Sandra" last="D Lfonso">Sandra D Lfonso</name><affiliation wicri:level="1"><nlm:aff id="A24">Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara</wicri:regionArea><wicri:noRegion>Novara</wicri:noRegion></affiliation></author><author><name sortKey="Martinelli Boneschi, Filippo" sort="Martinelli Boneschi, Filippo" uniqKey="Martinelli Boneschi F" first="Filippo" last="Martinelli-Boneschi">Filippo Martinelli-Boneschi</name><affiliation wicri:level="3"><nlm:aff id="A25">Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A26">Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Taylor, Bruce" sort="Taylor, Bruce" uniqKey="Taylor B" first="Bruce" last="Taylor">Bruce Taylor</name><affiliation wicri:level="1"><nlm:aff id="A27">Menzies Research Institute Tasmania, University of Tasmania, Tasmania, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Menzies Research Institute Tasmania, University of Tasmania, Tasmania</wicri:regionArea><wicri:noRegion>Tasmania</wicri:noRegion></affiliation></author><author><name sortKey="Harbo, Hanne F" sort="Harbo, Hanne F" uniqKey="Harbo H" first="Hanne F" last="Harbo">Hanne F. Harbo</name><affiliation wicri:level="3"><nlm:aff id="A28">Department of Neurology, Oslo University Hospital, Ullevål, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Neurology, Oslo University Hospital, Ullevål, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A29">University of Oslo, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Kockum, Ingrid" sort="Kockum, Ingrid" uniqKey="Kockum I" first="Ingrid" last="Kockum">Ingrid Kockum</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Hillert, Jan" sort="Hillert, Jan" uniqKey="Hillert J" first="Jan" last="Hillert">Jan Hillert</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Olsson, Tomas" sort="Olsson, Tomas" uniqKey="Olsson T" first="Tomas" last="Olsson">Tomas Olsson</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Ban, Maria" sort="Ban, Maria" uniqKey="Ban M" first="Maria" last="Ban">Maria Ban</name><affiliation wicri:level="4"><nlm:aff id="A9">Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Oksenberg, Jorge R" sort="Oksenberg, Jorge R" uniqKey="Oksenberg J" first="Jorge R" last="Oksenberg">Jorge R. Oksenberg</name><affiliation wicri:level="2"><nlm:aff id="A31">Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Hintzen, Rogier" sort="Hintzen, Rogier" uniqKey="Hintzen R" first="Rogier" last="Hintzen">Rogier Hintzen</name><affiliation wicri:level="3"><nlm:aff id="A32">Department of Neurology, MS Center ErasMS, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, MS Center ErasMS, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Barcellos, Lisa F" sort="Barcellos, Lisa F" uniqKey="Barcellos L" first="Lisa F" last="Barcellos">Lisa F. Barcellos</name><affiliation wicri:level="2"><nlm:aff id="A33">Division of Epidemiology, Genetic Epidemiology and Genomics Laboratory, School of Public Health, University of California, Berkeley, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology, Genetic Epidemiology and Genomics Laboratory, School of Public Health, University of California, Berkeley, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A34">California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A35">Kaiser Permanente Division of Research, Oakland, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Kaiser Permanente Division of Research, Oakland, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Agliardi, Cristina" sort="Agliardi, Cristina" uniqKey="Agliardi C" first="Cristina" last="Agliardi">Cristina Agliardi</name><affiliation wicri:level="3"><nlm:aff id="A37">Laboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi Foundation ONLUS, IRCCS S. Maria Nascente, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi Foundation ONLUS, IRCCS S. Maria Nascente, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Alfredsson, Lars" sort="Alfredsson, Lars" uniqKey="Alfredsson L" first="Lars" last="Alfredsson">Lars Alfredsson</name><affiliation wicri:level="3"><nlm:aff id="A38">Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Alizadeh, Mehdi" sort="Alizadeh, Mehdi" uniqKey="Alizadeh M" first="Mehdi" last="Alizadeh">Mehdi Alizadeh</name><affiliation wicri:level="3"><nlm:aff id="A39">Université Rennes 1, Rennes, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Université Rennes 1, Rennes</wicri:regionArea><placeName><region type="region">Région Bretagne</region><region type="old region">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Anderson, Carl" sort="Anderson, Carl" uniqKey="Anderson C" first="Carl" last="Anderson">Carl Anderson</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Andrews, Robert" sort="Andrews, Robert" uniqKey="Andrews R" first="Robert" last="Andrews">Robert Andrews</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="S Ndergaard, Helle Bach" sort="S Ndergaard, Helle Bach" uniqKey="S Ndergaard H" first="Helle Bach" last="S Ndergaard">Helle Bach S Ndergaard</name><affiliation wicri:level="3"><nlm:aff id="A16">Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Baker, Amie" sort="Baker, Amie" uniqKey="Baker A" first="Amie" last="Baker">Amie Baker</name><affiliation wicri:level="4"><nlm:aff id="A9">Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Band, Gavin" sort="Band, Gavin" uniqKey="Band G" first="Gavin" last="Band">Gavin Band</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Baranzini, Sergio E" sort="Baranzini, Sergio E" uniqKey="Baranzini S" first="Sergio E" last="Baranzini">Sergio E. Baranzini</name><affiliation wicri:level="2"><nlm:aff id="A31">Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Barizzone, Nadia" sort="Barizzone, Nadia" uniqKey="Barizzone N" first="Nadia" last="Barizzone">Nadia Barizzone</name><affiliation wicri:level="1"><nlm:aff id="A24">Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara</wicri:regionArea><wicri:noRegion>Novara</wicri:noRegion></affiliation></author><author><name sortKey="Barrett, Jeffrey" sort="Barrett, Jeffrey" uniqKey="Barrett J" first="Jeffrey" last="Barrett">Jeffrey Barrett</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Bellenguez, Celine" sort="Bellenguez, Celine" uniqKey="Bellenguez C" first="Céline" last="Bellenguez">Céline Bellenguez</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Bergamaschi, Laura" sort="Bergamaschi, Laura" uniqKey="Bergamaschi L" first="Laura" last="Bergamaschi">Laura Bergamaschi</name><affiliation wicri:level="1"><nlm:aff id="A24">Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara</wicri:regionArea><wicri:noRegion>Novara</wicri:noRegion></affiliation></author><author><name sortKey="Bernardinelli, Luisa" sort="Bernardinelli, Luisa" uniqKey="Bernardinelli L" first="Luisa" last="Bernardinelli">Luisa Bernardinelli</name><affiliation wicri:level="1"><nlm:aff id="A40">Medical Research Council Biostatistics Unit, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council Biostatistics Unit, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Berthele, Achim" sort="Berthele, Achim" uniqKey="Berthele A" first="Achim" last="Berthele">Achim Berthele</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Biberacher, Viola" sort="Biberacher, Viola" uniqKey="Biberacher V" first="Viola" last="Biberacher">Viola Biberacher</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Binder, Thomas M C" sort="Binder, Thomas M C" uniqKey="Binder T" first="Thomas M C" last="Binder">Thomas M C. Binder</name><affiliation wicri:level="3"><nlm:aff id="A41">Department of Transfusion Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Transfusion Medicine, University Medical Center Hamburg-Eppendorf, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Blackburn, Hannah" sort="Blackburn, Hannah" uniqKey="Blackburn H" first="Hannah" last="Blackburn">Hannah Blackburn</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Bomfim, Izaura L" sort="Bomfim, Izaura L" uniqKey="Bomfim I" first="Izaura L" last="Bomfim">Izaura L. Bomfim</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Brambilla, Paola" sort="Brambilla, Paola" uniqKey="Brambilla P" first="Paola" last="Brambilla">Paola Brambilla</name><affiliation wicri:level="3"><nlm:aff id="A25">Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Broadley, Simon" sort="Broadley, Simon" uniqKey="Broadley S" first="Simon" last="Broadley">Simon Broadley</name><affiliation wicri:level="1"><nlm:aff id="A42">School of Medicine, Griffith University, Gold Coast, Queensland, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Medicine, Griffith University, Gold Coast, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Brochet, Bruno" sort="Brochet, Bruno" uniqKey="Brochet B" first="Bruno" last="Brochet">Bruno Brochet</name><affiliation wicri:level="3"><nlm:aff id="A43">CHU Pellegrin, Université Bordeaux 2, Bordeaux, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>CHU Pellegrin, Université Bordeaux 2, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Brundin, Lou" sort="Brundin, Lou" uniqKey="Brundin L" first="Lou" last="Brundin">Lou Brundin</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Buck, Dorothea" sort="Buck, Dorothea" uniqKey="Buck D" first="Dorothea" last="Buck">Dorothea Buck</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Butzkueven, Helmut" sort="Butzkueven, Helmut" uniqKey="Butzkueven H" first="Helmut" last="Butzkueven">Helmut Butzkueven</name><affiliation wicri:level="4"><nlm:aff id="A44">University of Melbourne, Victoria, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>University of Melbourne, Victoria, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A45">Department of Neurology, Box Hill Hospital, Monash University, Victoria, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Neurology, Box Hill Hospital, Monash University, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Caillier, Stacy J" sort="Caillier, Stacy J" uniqKey="Caillier S" first="Stacy J" last="Caillier">Stacy J. Caillier</name><affiliation wicri:level="2"><nlm:aff id="A31">Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Camu, William" sort="Camu, William" uniqKey="Camu W" first="William" last="Camu">William Camu</name><affiliation wicri:level="3"><nlm:aff id="A46">Service de Neurologie, CHRU Montpellier, Montpellier, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, CHRU Montpellier, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Carpentier, Wassila" sort="Carpentier, Wassila" uniqKey="Carpentier W" first="Wassila" last="Carpentier">Wassila Carpentier</name><affiliation wicri:level="3"><nlm:aff id="A47">Plateforme Post-Génomique P3S, UPMC-INSERM, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Plateforme Post-Génomique P3S, UPMC-INSERM, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Cavalla, Paola" sort="Cavalla, Paola" uniqKey="Cavalla P" first="Paola" last="Cavalla">Paola Cavalla</name><affiliation wicri:level="3"><nlm:aff id="A48">Department of Neuroscience, MS Center, Azienda ospedaliera Città della Salute e della Scienza di Torino, Turin, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neuroscience, MS Center, Azienda ospedaliera Città della Salute e della Scienza di Torino, Turin</wicri:regionArea><placeName><settlement type="city">Turin</settlement><region type="région" nuts="2">Piémont</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A49">University of Turin, Turin, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>University of Turin, Turin</wicri:regionArea><placeName><settlement type="city">Turin</settlement><region type="région" nuts="2">Piémont</region></placeName></affiliation></author><author><name sortKey="Celius, Elisabeth G" sort="Celius, Elisabeth G" uniqKey="Celius E" first="Elisabeth G" last="Celius">Elisabeth G. Celius</name><affiliation wicri:level="3"><nlm:aff id="A28">Department of Neurology, Oslo University Hospital, Ullevål, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Neurology, Oslo University Hospital, Ullevål, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Coman, Irene" sort="Coman, Irene" uniqKey="Coman I" first="Irène" last="Coman">Irène Coman</name><affiliation wicri:level="3"><nlm:aff id="A50">Service de Neurologie, Hôpital Avicenne, Bobigny, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, Hôpital Avicenne, Bobigny</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Bobigny</settlement></placeName></affiliation></author><author><name sortKey="Comi, Giancarlo" sort="Comi, Giancarlo" uniqKey="Comi G" first="Giancarlo" last="Comi">Giancarlo Comi</name><affiliation wicri:level="3"><nlm:aff id="A25">Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A26">Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Corrado, Lucia" sort="Corrado, Lucia" uniqKey="Corrado L" first="Lucia" last="Corrado">Lucia Corrado</name><affiliation wicri:level="1"><nlm:aff id="A24">Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara</wicri:regionArea><wicri:noRegion>Novara</wicri:noRegion></affiliation></author><author><name sortKey="Cosemans, Leentje" sort="Cosemans, Leentje" uniqKey="Cosemans L" first="Leentje" last="Cosemans">Leentje Cosemans</name><affiliation wicri:level="1"><nlm:aff id="A15">Section of Experimental Neurology, Laboratory for Neuroimmunology, KU Leuven, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Section of Experimental Neurology, Laboratory for Neuroimmunology, KU Leuven, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Cournu Rebeix, Isabelle" sort="Cournu Rebeix, Isabelle" uniqKey="Cournu Rebeix I" first="Isabelle" last="Cournu-Rebeix">Isabelle Cournu-Rebeix</name><affiliation wicri:level="3"><nlm:aff id="A18">Département de Neurologie, INSERM UMR S 975 CRICM, UPMC, Pitié-Salpêtrière, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Département de Neurologie, INSERM UMR S 975 CRICM, UPMC, Pitié-Salpêtrière, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Cree, Bruce A C" sort="Cree, Bruce A C" uniqKey="Cree B" first="Bruce A C" last="Cree">Bruce A C. Cree</name><affiliation wicri:level="2"><nlm:aff id="A31">Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Cusi, Daniele" sort="Cusi, Daniele" uniqKey="Cusi D" first="Daniele" last="Cusi">Daniele Cusi</name><affiliation wicri:level="3"><nlm:aff id="A51">Department of Health Sciences, San Paolo Hospital and Filarete Foundation, University of Milan, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Sciences, San Paolo Hospital and Filarete Foundation, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Damotte, Vincent" sort="Damotte, Vincent" uniqKey="Damotte V" first="Vincent" last="Damotte">Vincent Damotte</name><affiliation wicri:level="3"><nlm:aff id="A18">Département de Neurologie, INSERM UMR S 975 CRICM, UPMC, Pitié-Salpêtrière, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Département de Neurologie, INSERM UMR S 975 CRICM, UPMC, Pitié-Salpêtrière, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Defer, Gilles" sort="Defer, Gilles" uniqKey="Defer G" first="Gilles" last="Defer">Gilles Defer</name><affiliation wicri:level="3"><nlm:aff id="A52">Service de Neurologie, CHU de Caen and INSERM U 919-GIP Cyceron, Caen, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, CHU de Caen and INSERM U 919-GIP Cyceron, Caen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Basse-Normandie</region><settlement type="city">Caen</settlement></placeName></affiliation></author><author><name sortKey="Delgado, Silvia R" sort="Delgado, Silvia R" uniqKey="Delgado S" first="Silvia R" last="Delgado">Silvia R. Delgado</name><affiliation wicri:level="2"><nlm:aff id="A53">Department of Neurology, Multiple Sclerosis Division, Miller School of Medicine, University of Miami, Miami, Florida, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Multiple Sclerosis Division, Miller School of Medicine, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Deloukas, Panos" sort="Deloukas, Panos" uniqKey="Deloukas P" first="Panos" last="Deloukas">Panos Deloukas</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Di Sapio, Alessia" sort="Di Sapio, Alessia" uniqKey="Di Sapio A" first="Alessia" last="Di Sapio">Alessia Di Sapio</name><affiliation wicri:level="3"><nlm:aff id="A54">Neurologia 2 - CRESM, AOU San Luigi, Orbassano, Turin, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Neurologia 2 - CRESM, AOU San Luigi, Orbassano, Turin</wicri:regionArea><placeName><settlement type="city">Turin</settlement><region type="région" nuts="2">Piémont</region></placeName></affiliation></author><author><name sortKey="Dilthey, Alexander T" sort="Dilthey, Alexander T" uniqKey="Dilthey A" first="Alexander T" last="Dilthey">Alexander T. Dilthey</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Donnelly, Peter" sort="Donnelly, Peter" uniqKey="Donnelly P" first="Peter" last="Donnelly">Peter Donnelly</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Dubois, Benedicte" sort="Dubois, Benedicte" uniqKey="Dubois B" first="Bénédicte" last="Dubois">Bénédicte Dubois</name><affiliation wicri:level="1"><nlm:aff id="A15">Section of Experimental Neurology, Laboratory for Neuroimmunology, KU Leuven, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Section of Experimental Neurology, Laboratory for Neuroimmunology, KU Leuven, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Duddy, Martin" sort="Duddy, Martin" uniqKey="Duddy M" first="Martin" last="Duddy">Martin Duddy</name><affiliation wicri:level="1"><nlm:aff id="A55">Department of Neurology, Royal Victoria Infirmary, Newcastle upon Tyne, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Royal Victoria Infirmary, Newcastle upon Tyne</wicri:regionArea><wicri:noRegion>Newcastle upon Tyne</wicri:noRegion></affiliation></author><author><name sortKey="Edkins, Sarah" sort="Edkins, Sarah" uniqKey="Edkins S" first="Sarah" last="Edkins">Sarah Edkins</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Elovaara, Irina" sort="Elovaara, Irina" uniqKey="Elovaara I" first="Irina" last="Elovaara">Irina Elovaara</name><affiliation wicri:level="1"><nlm:aff id="A56">Department of Neurology, University of Tampere, Medical School, Tampere, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Neurology, University of Tampere, Medical School, Tampere</wicri:regionArea><wicri:noRegion>Tampere</wicri:noRegion></affiliation></author><author><name sortKey="Esposito, Federica" sort="Esposito, Federica" uniqKey="Esposito F" first="Federica" last="Esposito">Federica Esposito</name><affiliation wicri:level="3"><nlm:aff id="A25">Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A26">Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Evangelou, Nikos" sort="Evangelou, Nikos" uniqKey="Evangelou N" first="Nikos" last="Evangelou">Nikos Evangelou</name><affiliation wicri:level="1"><nlm:aff id="A57">Division of Clinical Neurology, Nottingham University Hospital, Nottingham, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Clinical Neurology, Nottingham University Hospital, Nottingham</wicri:regionArea><wicri:noRegion>Nottingham</wicri:noRegion></affiliation></author><author><name sortKey="Fiddes, Barnaby" sort="Fiddes, Barnaby" uniqKey="Fiddes B" first="Barnaby" last="Fiddes">Barnaby Fiddes</name><affiliation wicri:level="4"><nlm:aff id="A9">Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Field, Judith" sort="Field, Judith" uniqKey="Field J" first="Judith" last="Field">Judith Field</name><affiliation wicri:level="4"><nlm:aff id="A58">Florey Institute of Neuroscience and Mental Health, University of Melbourne, Victoria, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Florey Institute of Neuroscience and Mental Health, University of Melbourne, Victoria</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Franke, Andre" sort="Franke, Andre" uniqKey="Franke A" first="Andre" last="Franke">Andre Franke</name><affiliation wicri:level="3"><nlm:aff id="A59">Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Freeman, Colin" sort="Freeman, Colin" uniqKey="Freeman C" first="Colin" last="Freeman">Colin Freeman</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Frohlich, Irene Y" sort="Frohlich, Irene Y" uniqKey="Frohlich I" first="Irene Y" last="Frohlich">Irene Y. Frohlich</name><affiliation wicri:level="2"><nlm:aff id="A2">Department of Neurology, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Brigham & Women’s Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Brigham & Women’s Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Galimberti, Daniela" sort="Galimberti, Daniela" uniqKey="Galimberti D" first="Daniela" last="Galimberti">Daniela Galimberti</name><affiliation wicri:level="3"><nlm:aff id="A60">Department of Pathophysiology and Transplantation, Neurology Unit, University of Milan, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Pathophysiology and Transplantation, Neurology Unit, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A61">Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:aff id="A62">KORAgen, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Institute of Genetic Epidemiology, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>KORAgen, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Institute of Genetic Epidemiology, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Gourraud, Pierre Antoine" sort="Gourraud, Pierre Antoine" uniqKey="Gourraud P" first="Pierre-Antoine" last="Gourraud">Pierre-Antoine Gourraud</name><affiliation wicri:level="2"><nlm:aff id="A31">Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Graetz, Christiane" sort="Graetz, Christiane" uniqKey="Graetz C" first="Christiane" last="Graetz">Christiane Graetz</name><affiliation wicri:level="3"><nlm:aff id="A23">Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz</wicri:regionArea><placeName><region type="land" nuts="2">Rhénanie-Palatinat</region><settlement type="city">Mayence</settlement></placeName></affiliation></author><author><name sortKey="Graham, Andrew" sort="Graham, Andrew" uniqKey="Graham A" first="Andrew" last="Graham">Andrew Graham</name><affiliation wicri:level="1"><nlm:aff id="A63">Department of Clinical Neurology, The Ipswich Hospital NHS Trust, Ipswich, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurology, The Ipswich Hospital NHS Trust, Ipswich</wicri:regionArea><wicri:noRegion>Ipswich</wicri:noRegion></affiliation></author><author><name sortKey="Grummel, Verena" sort="Grummel, Verena" uniqKey="Grummel V" first="Verena" last="Grummel">Verena Grummel</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Guaschino, Clara" sort="Guaschino, Clara" uniqKey="Guaschino C" first="Clara" last="Guaschino">Clara Guaschino</name><affiliation wicri:level="3"><nlm:aff id="A25">Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A26">Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Hadjixenofontos, Athena" sort="Hadjixenofontos, Athena" uniqKey="Hadjixenofontos A" first="Athena" last="Hadjixenofontos">Athena Hadjixenofontos</name><affiliation wicri:level="2"><nlm:aff id="A1">John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Hakonarson, Hakon" sort="Hakonarson, Hakon" uniqKey="Hakonarson H" first="Hakon" last="Hakonarson">Hakon Hakonarson</name><affiliation wicri:level="2"><nlm:aff id="A64">Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A65">Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Halfpenny, Christopher" sort="Halfpenny, Christopher" uniqKey="Halfpenny C" first="Christopher" last="Halfpenny">Christopher Halfpenny</name><affiliation wicri:level="1"><nlm:aff id="A66">Wellcome Trust Clinical Research Facility, Southampton General Hospital, Southampton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Clinical Research Facility, Southampton General Hospital, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation></author><author><name sortKey="Hall, Gillian" sort="Hall, Gillian" uniqKey="Hall G" first="Gillian" last="Hall">Gillian Hall</name><affiliation wicri:level="1"><nlm:aff id="A67">Department of Neurology, Aberdeen Royal Infirmary, Aberdeen, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Aberdeen Royal Infirmary, Aberdeen</wicri:regionArea><wicri:noRegion>Aberdeen</wicri:noRegion></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation wicri:level="3"><nlm:aff id="A68">Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name><affiliation wicri:level="3"><nlm:aff id="A69">Department of Medicine at Karolinska University Hospital Solna, Atherosclerosis Research Unit, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medicine at Karolinska University Hospital Solna, Atherosclerosis Research Unit, Center for Molecular Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Harley, James" sort="Harley, James" uniqKey="Harley J" first="James" last="Harley">James Harley</name><affiliation wicri:level="1"><nlm:aff id="A70">Department of Neurology, Hull Royal Infirmary, Hull, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Hull Royal Infirmary, Hull</wicri:regionArea><wicri:noRegion>Hull</wicri:noRegion></affiliation></author><author><name sortKey="Harrower, Timothy" sort="Harrower, Timothy" uniqKey="Harrower T" first="Timothy" last="Harrower">Timothy Harrower</name><affiliation wicri:level="1"><nlm:aff id="A71">Department of Neurology, Royal Devon and Exeter Foundaton Trust Hospital, Exeter, Devon, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Royal Devon and Exeter Foundaton Trust Hospital, Exeter, Devon</wicri:regionArea><wicri:noRegion>Devon</wicri:noRegion></affiliation></author><author><name sortKey="Hawkins, Clive" sort="Hawkins, Clive" uniqKey="Hawkins C" first="Clive" last="Hawkins">Clive Hawkins</name><affiliation wicri:level="1"><nlm:aff id="A72">Keele University Medical School, University Hospital of North Staffordshire, Stoke-on-Trent, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Keele University Medical School, University Hospital of North Staffordshire, Stoke-on-Trent</wicri:regionArea><wicri:noRegion>Stoke-on-Trent</wicri:noRegion></affiliation></author><author><name sortKey="Hellenthal, Garrett" sort="Hellenthal, Garrett" uniqKey="Hellenthal G" first="Garrett" last="Hellenthal">Garrett Hellenthal</name><affiliation wicri:level="4"><nlm:aff id="A73">UCL Genetics Institute (UGI), University College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>UCL Genetics Institute (UGI), University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Hillier, Charles" sort="Hillier, Charles" uniqKey="Hillier C" first="Charles" last="Hillier">Charles Hillier</name><affiliation wicri:level="1"><nlm:aff id="A74">Department of Neurology, Poole General Hospital, Poole, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Poole General Hospital, Poole</wicri:regionArea><wicri:noRegion>Poole</wicri:noRegion></affiliation></author><author><name sortKey="Hobart, Jeremy" sort="Hobart, Jeremy" uniqKey="Hobart J" first="Jeremy" last="Hobart">Jeremy Hobart</name><affiliation wicri:level="1"><nlm:aff id="A75">Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth</wicri:regionArea><wicri:noRegion>Plymouth</wicri:noRegion></affiliation></author><author><name sortKey="Hoshi, Muni" sort="Hoshi, Muni" uniqKey="Hoshi M" first="Muni" last="Hoshi">Muni Hoshi</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Hunt, Sarah E" sort="Hunt, Sarah E" uniqKey="Hunt S" first="Sarah E" last="Hunt">Sarah E. Hunt</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Jagodic, Maja" sort="Jagodic, Maja" uniqKey="Jagodic M" first="Maja" last="Jagodic">Maja Jagodic</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Jel I, Ilijas" sort="Jel I, Ilijas" uniqKey="Jel I I" first="Ilijas" last="Jel I">Ilijas Jel I</name><affiliation wicri:level="3"><nlm:aff id="A76">Institute for Neuroimmunology and Clinical MS Research (inims), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Neuroimmunology and Clinical MS Research (inims), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A77">Department of Neuroimmunology and MS Research, Neurology Clinic, University Hospital Zürich, Zürich, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Neuroimmunology and MS Research, Neurology Clinic, University Hospital Zürich, Zürich</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName></affiliation></author><author><name sortKey="Jochim, Angela" sort="Jochim, Angela" uniqKey="Jochim A" first="Angela" last="Jochim">Angela Jochim</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Kendall, Brian" sort="Kendall, Brian" uniqKey="Kendall B" first="Brian" last="Kendall">Brian Kendall</name><affiliation wicri:level="1"><nlm:aff id="A78">Department of Neurology, Division of Clinical Neurology, Leicester Royal Infirmary, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Division of Clinical Neurology, Leicester Royal Infirmary, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation></author><author><name sortKey="Kermode, Allan" sort="Kermode, Allan" uniqKey="Kermode A" first="Allan" last="Kermode">Allan Kermode</name><affiliation wicri:level="1"><nlm:aff id="A79">Australian Neuromuscular Research Institute, University of Western Australia, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Australian Neuromuscular Research Institute, University of Western Australia, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A80">Murdoch University, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Murdoch University, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Kilpatrick, Trevor" sort="Kilpatrick, Trevor" uniqKey="Kilpatrick T" first="Trevor" last="Kilpatrick">Trevor Kilpatrick</name><affiliation wicri:level="4"><nlm:aff id="A81">Melbourne Neuroscience Institute, University of Melbourne, Victoria, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Melbourne Neuroscience Institute, University of Melbourne, Victoria</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Koivisto, Keijo" sort="Koivisto, Keijo" uniqKey="Koivisto K" first="Keijo" last="Koivisto">Keijo Koivisto</name><affiliation wicri:level="1"><nlm:aff id="A82">Department of Neurology, Seinäjoki Central Hospital, Seinäjoki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Neurology, Seinäjoki Central Hospital, Seinäjoki</wicri:regionArea><wicri:noRegion>Seinäjoki</wicri:noRegion></affiliation></author><author><name sortKey="Konidari, Ioanna" sort="Konidari, Ioanna" uniqKey="Konidari I" first="Ioanna" last="Konidari">Ioanna Konidari</name><affiliation wicri:level="2"><nlm:aff id="A1">John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Korn, Thomas" sort="Korn, Thomas" uniqKey="Korn T" first="Thomas" last="Korn">Thomas Korn</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Kronsbein, Helena" sort="Kronsbein, Helena" uniqKey="Kronsbein H" first="Helena" last="Kronsbein">Helena Kronsbein</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Langford, Cordelia" sort="Langford, Cordelia" uniqKey="Langford C" first="Cordelia" last="Langford">Cordelia Langford</name><affiliation wicri:level="1"><nlm:aff id="A13">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Larsson, Malin" sort="Larsson, Malin" uniqKey="Larsson M" first="Malin" last="Larsson">Malin Larsson</name><affiliation wicri:level="1"><nlm:aff id="A83">IFM Bioinformatics, Linköping University, Linköping, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>IFM Bioinformatics, Linköping University, Linköping</wicri:regionArea><wicri:noRegion>Linköping</wicri:noRegion></affiliation></author><author><name sortKey="Lathrop, Mark" sort="Lathrop, Mark" uniqKey="Lathrop M" first="Mark" last="Lathrop">Mark Lathrop</name><affiliation wicri:level="3"><nlm:aff id="A84">Fondation Jean Dausset - Centre d’Etude du Polymorphisme Humain, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Fondation Jean Dausset - Centre d’Etude du Polymorphisme Humain, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A85">Commissariat à l’Energie Atomique, Institut Genomique, Centre National de Génotypage, Evry, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Commissariat à l’Energie Atomique, Institut Genomique, Centre National de Génotypage, Evry</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Évry (Essonne)</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A86">McGill University and Genome Quebec Innovation Center, Montreal, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>McGill University and Genome Quebec Innovation Center, Montreal</wicri:regionArea><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Lebrun Frenay, Christine" sort="Lebrun Frenay, Christine" uniqKey="Lebrun Frenay C" first="Christine" last="Lebrun-Frenay">Christine Lebrun-Frenay</name><affiliation wicri:level="1"><nlm:aff id="A87">Service de Neurologie, Hôpital Pasteur, CHRU Nice, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, Hôpital Pasteur, CHRU Nice</wicri:regionArea><wicri:noRegion>CHRU Nice</wicri:noRegion><wicri:noRegion>CHRU Nice</wicri:noRegion></affiliation></author><author><name sortKey="Lechner Scott, Jeannette" sort="Lechner Scott, Jeannette" uniqKey="Lechner Scott J" first="Jeannette" last="Lechner-Scott">Jeannette Lechner-Scott</name><affiliation wicri:level="1"><nlm:aff id="A88">Hunter Medical Research Institute, University of Newcastle, New South Wales, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Hunter Medical Research Institute, University of Newcastle, New South Wales</wicri:regionArea><wicri:noRegion>New South Wales</wicri:noRegion></affiliation></author><author><name sortKey="Lee, Michelle H" sort="Lee, Michelle H" uniqKey="Lee M" first="Michelle H" last="Lee">Michelle H. Lee</name><affiliation wicri:level="2"><nlm:aff id="A2">Department of Neurology, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Brigham & Women’s Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Brigham & Women’s Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Leone, Maurizio A" sort="Leone, Maurizio A" uniqKey="Leone M" first="Maurizio A" last="Leone">Maurizio A. Leone</name><affiliation wicri:level="1"><nlm:aff id="A89">Department of Neurology, Ospedale Maggiore, Novara, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Ospedale Maggiore, Novara</wicri:regionArea><wicri:noRegion>Novara</wicri:noRegion></affiliation></author><author><name sortKey="Lepp, Virpi" sort="Lepp, Virpi" uniqKey="Lepp V" first="Virpi" last="Lepp">Virpi Lepp</name><affiliation wicri:level="4"><nlm:aff id="A17">Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Liberatore, Giuseppe" sort="Liberatore, Giuseppe" uniqKey="Liberatore G" first="Giuseppe" last="Liberatore">Giuseppe Liberatore</name><affiliation wicri:level="3"><nlm:aff id="A25">Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A26">Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Lie, Benedicte A" sort="Lie, Benedicte A" uniqKey="Lie B" first="Benedicte A" last="Lie">Benedicte A. Lie</name><affiliation wicri:level="3"><nlm:aff id="A29">University of Oslo, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A90">Department of Medical Genetics, Oslo University Hospital, Ullevål, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Medical Genetics, Oslo University Hospital, Ullevål, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Lill, Christina M" sort="Lill, Christina M" uniqKey="Lill C" first="Christina M" last="Lill">Christina M. Lill</name><affiliation wicri:level="3"><nlm:aff id="A23">Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz</wicri:regionArea><placeName><region type="land" nuts="2">Rhénanie-Palatinat</region><settlement type="city">Mayence</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A91">Department of Vertebrate Genomics, Neuropsychiatric Genetics Group, Max Planck Institute for Molecular Genetics, Berlin, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Vertebrate Genomics, Neuropsychiatric Genetics Group, Max Planck Institute for Molecular Genetics, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Linden, Magdalena" sort="Linden, Magdalena" uniqKey="Linden M" first="Magdalena" last="Lindén">Magdalena Lindén</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Link, Jenny" sort="Link, Jenny" uniqKey="Link J" first="Jenny" last="Link">Jenny Link</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Luessi, Felix" sort="Luessi, Felix" uniqKey="Luessi F" first="Felix" last="Luessi">Felix Luessi</name><affiliation wicri:level="3"><nlm:aff id="A23">Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz</wicri:regionArea><placeName><region type="land" nuts="2">Rhénanie-Palatinat</region><settlement type="city">Mayence</settlement></placeName></affiliation></author><author><name sortKey="Lycke, Jan" sort="Lycke, Jan" uniqKey="Lycke J" first="Jan" last="Lycke">Jan Lycke</name><affiliation wicri:level="1"><nlm:aff id="A92">Department of Clinical Neurosciences and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Göteborgs Universitet, Göteborg, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neurosciences and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Göteborgs Universitet, Göteborg</wicri:regionArea><wicri:noRegion>Göteborg</wicri:noRegion></affiliation></author><author><name sortKey="Macciardi, Fabio" sort="Macciardi, Fabio" uniqKey="Macciardi F" first="Fabio" last="Macciardi">Fabio Macciardi</name><affiliation wicri:level="2"><nlm:aff id="A93">Department of Psychiatry and Human Behavior, School of Medicine, University of California, Irvine, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry and Human Behavior, School of Medicine, University of California, Irvine, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A94">Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="M Nnisto, Satu" sort="M Nnisto, Satu" uniqKey="M Nnisto S" first="Satu" last="M Nnistö">Satu M Nnistö</name><affiliation wicri:level="1"><nlm:aff id="A95">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Manrique, Clara P" sort="Manrique, Clara P" uniqKey="Manrique C" first="Clara P" last="Manrique">Clara P. Manrique</name><affiliation wicri:level="2"><nlm:aff id="A1">John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Martin, Roland" sort="Martin, Roland" uniqKey="Martin R" first="Roland" last="Martin">Roland Martin</name><affiliation wicri:level="3"><nlm:aff id="A76">Institute for Neuroimmunology and Clinical MS Research (inims), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Neuroimmunology and Clinical MS Research (inims), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A77">Department of Neuroimmunology and MS Research, Neurology Clinic, University Hospital Zürich, Zürich, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Neuroimmunology and MS Research, Neurology Clinic, University Hospital Zürich, Zürich</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName></affiliation></author><author><name sortKey="Martinelli, Vittorio" sort="Martinelli, Vittorio" uniqKey="Martinelli V" first="Vittorio" last="Martinelli">Vittorio Martinelli</name><affiliation wicri:level="3"><nlm:aff id="A26">Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Mason, Deborah" sort="Mason, Deborah" uniqKey="Mason D" first="Deborah" last="Mason">Deborah Mason</name><affiliation wicri:level="1"><nlm:aff id="A96">Canterbury District Health Board, Christchurch, New Zealand</nlm:aff><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Canterbury District Health Board, Christchurch</wicri:regionArea><wicri:noRegion>Christchurch</wicri:noRegion></affiliation></author><author><name sortKey="Mazibrada, Gordon" sort="Mazibrada, Gordon" uniqKey="Mazibrada G" first="Gordon" last="Mazibrada">Gordon Mazibrada</name><affiliation wicri:level="3"><nlm:aff id="A97">Department of Neurology, Queen Elizabeth Medical Centre, Edgbaston, Birmingham, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Queen Elizabeth Medical Centre, Edgbaston, Birmingham</wicri:regionArea><placeName><settlement type="city">Birmingham</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Midlands de l'Ouest</region></placeName></affiliation></author><author><name sortKey="Mccabe, Cristin" sort="Mccabe, Cristin" uniqKey="Mccabe C" first="Cristin" last="Mccabe">Cristin Mccabe</name><affiliation wicri:level="2"><nlm:aff id="A10">Program in Medical and Population Genetics, Broad Institute of Harvard University and MIT, Cambridge, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard University and MIT, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Mero, Inger Lise" sort="Mero, Inger Lise" uniqKey="Mero I" first="Inger-Lise" last="Mero">Inger-Lise Mero</name><affiliation wicri:level="3"><nlm:aff id="A28">Department of Neurology, Oslo University Hospital, Ullevål, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Neurology, Oslo University Hospital, Ullevål, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A29">University of Oslo, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A90">Department of Medical Genetics, Oslo University Hospital, Ullevål, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Medical Genetics, Oslo University Hospital, Ullevål, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Mescheriakova, Julia" sort="Mescheriakova, Julia" uniqKey="Mescheriakova J" first="Julia" last="Mescheriakova">Julia Mescheriakova</name><affiliation wicri:level="3"><nlm:aff id="A32">Department of Neurology, MS Center ErasMS, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology, MS Center ErasMS, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Moutsianas, Loukas" sort="Moutsianas, Loukas" uniqKey="Moutsianas L" first="Loukas" last="Moutsianas">Loukas Moutsianas</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Myhr, Kjell Morten" sort="Myhr, Kjell Morten" uniqKey="Myhr K" first="Kjell-Morten" last="Myhr">Kjell-Morten Myhr</name><affiliation wicri:level="1"><nlm:aff id="A98">Department of Neurology, The Norwegian Multiple Sclerosis Registry and Biobank, Haukeland University Hospital, Bergen, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Neurology, The Norwegian Multiple Sclerosis Registry and Biobank, Haukeland University Hospital, Bergen</wicri:regionArea><wicri:noRegion>Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Nagels, Guy" sort="Nagels, Guy" uniqKey="Nagels G" first="Guy" last="Nagels">Guy Nagels</name><affiliation wicri:level="1"><nlm:aff id="A99">National Multiple Sclerosis Center Melsbroek, Melsbroek, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>National Multiple Sclerosis Center Melsbroek, Melsbroek</wicri:regionArea><wicri:noRegion>Melsbroek</wicri:noRegion></affiliation></author><author><name sortKey="Nicholas, Richard" sort="Nicholas, Richard" uniqKey="Nicholas R" first="Richard" last="Nicholas">Richard Nicholas</name><affiliation wicri:level="3"><nlm:aff id="A100">Neurology Department, Charing Cross Hospital, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Neurology Department, Charing Cross Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Nilsson, Petra" sort="Nilsson, Petra" uniqKey="Nilsson P" first="Petra" last="Nilsson">Petra Nilsson</name><affiliation wicri:level="1"><nlm:aff id="A101">Department of Clinical Sciences, Lund University, Lund, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Sciences, Lund University, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name sortKey="Piehl, Fredrik" sort="Piehl, Fredrik" uniqKey="Piehl F" first="Fredrik" last="Piehl">Fredrik Piehl</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Pirinen, Matti" sort="Pirinen, Matti" uniqKey="Pirinen M" first="Matti" last="Pirinen">Matti Pirinen</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Price, Sian E" sort="Price, Sian E" uniqKey="Price S" first="Siân E" last="Price">Siân E. Price</name><affiliation wicri:level="1"><nlm:aff id="A102">Department of Neurology, Royal Hallamshire Hospital, Sheffield, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Royal Hallamshire Hospital, Sheffield</wicri:regionArea><wicri:noRegion>Sheffield</wicri:noRegion></affiliation></author><author><name sortKey="Quach, Hong" sort="Quach, Hong" uniqKey="Quach H" first="Hong" last="Quach">Hong Quach</name><affiliation wicri:level="2"><nlm:aff id="A33">Division of Epidemiology, Genetic Epidemiology and Genomics Laboratory, School of Public Health, University of California, Berkeley, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology, Genetic Epidemiology and Genomics Laboratory, School of Public Health, University of California, Berkeley, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Reunanen, Mauri" sort="Reunanen, Mauri" uniqKey="Reunanen M" first="Mauri" last="Reunanen">Mauri Reunanen</name><affiliation wicri:level="1"><nlm:aff id="A103">Department of Neurology, University of Oulu, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Neurology, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A104">Department of Neurology, University Hospital of Oulu, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Neurology, University Hospital of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Robberecht, Wim" sort="Robberecht, Wim" uniqKey="Robberecht W" first="Wim" last="Robberecht">Wim Robberecht</name><affiliation wicri:level="1"><nlm:aff id="A105">Laboratory of Neurobiology, Vesalius Research Center, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Laboratory of Neurobiology, Vesalius Research Center, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A106">Experimental Neurology, Leuven Research Institute for Neurodegenerative Diseases (LIND), University of Leuven (KU Leuven), Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Experimental Neurology, Leuven Research Institute for Neurodegenerative Diseases (LIND), University of Leuven (KU Leuven), Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A107">Department of Neurology, University Hospitals Leuven, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Neurology, University Hospitals Leuven, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Robertson, Neil P" sort="Robertson, Neil P" uniqKey="Robertson N" first="Neil P" last="Robertson">Neil P. Robertson</name><affiliation wicri:level="1"><nlm:aff id="A108">Institute of Psychological Medicine and Clinical Neuroscience, Cardiff University, University Hospital of Wales, Cardiff, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neuroscience, Cardiff University, University Hospital of Wales, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Rodegher, Mariaemma" sort="Rodegher, Mariaemma" uniqKey="Rodegher M" first="Mariaemma" last="Rodegher">Mariaemma Rodegher</name><affiliation wicri:level="3"><nlm:aff id="A26">Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Rog, David" sort="Rog, David" uniqKey="Rog D" first="David" last="Rog">David Rog</name><affiliation wicri:level="1"><nlm:aff id="A109">Department of Neurology, Greater Manchester Neurosciences Centre, Salford Royal NHS Foundation Trust, Salford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Greater Manchester Neurosciences Centre, Salford Royal NHS Foundation Trust, Salford</wicri:regionArea><wicri:noRegion>Salford</wicri:noRegion></affiliation></author><author><name sortKey="Salvetti, Marco" sort="Salvetti, Marco" uniqKey="Salvetti M" first="Marco" last="Salvetti">Marco Salvetti</name><affiliation wicri:level="3"><nlm:aff id="A110">Department of Neuroscience, Centre for Experimental Neurological Therapies, Mental Health and Sensory Organs, Sapienza Università di Roma, Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neuroscience, Centre for Experimental Neurological Therapies, Mental Health and Sensory Organs, Sapienza Università di Roma, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Schnetz Boutaud, Nathalie C" sort="Schnetz Boutaud, Nathalie C" uniqKey="Schnetz Boutaud N" first="Nathalie C" last="Schnetz-Boutaud">Nathalie C. Schnetz-Boutaud</name><affiliation wicri:level="2"><nlm:aff id="A8">Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Sellebjerg, Finn" sort="Sellebjerg, Finn" uniqKey="Sellebjerg F" first="Finn" last="Sellebjerg">Finn Sellebjerg</name><affiliation wicri:level="3"><nlm:aff id="A16">Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Selter, Rebecca C" sort="Selter, Rebecca C" uniqKey="Selter R" first="Rebecca C" last="Selter">Rebecca C. Selter</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Schaefer, Catherine" sort="Schaefer, Catherine" uniqKey="Schaefer C" first="Catherine" last="Schaefer">Catherine Schaefer</name><affiliation wicri:level="2"><nlm:aff id="A35">Kaiser Permanente Division of Research, Oakland, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Kaiser Permanente Division of Research, Oakland, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Shaunak, Sandip" sort="Shaunak, Sandip" uniqKey="Shaunak S" first="Sandip" last="Shaunak">Sandip Shaunak</name><affiliation wicri:level="1"><nlm:aff id="A111">Department of Neurology, Royal Preston Hospital, Preston, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Royal Preston Hospital, Preston</wicri:regionArea><wicri:noRegion>Preston</wicri:noRegion></affiliation></author><author><name sortKey="Shen, Ling" sort="Shen, Ling" uniqKey="Shen L" first="Ling" last="Shen">Ling Shen</name><affiliation wicri:level="2"><nlm:aff id="A35">Kaiser Permanente Division of Research, Oakland, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Kaiser Permanente Division of Research, Oakland, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Shields, Simon" sort="Shields, Simon" uniqKey="Shields S" first="Simon" last="Shields">Simon Shields</name><affiliation wicri:level="1"><nlm:aff id="A112">Department of Neurology, Norfolk and Norwich Hospital, Norwich, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Norfolk and Norwich Hospital, Norwich</wicri:regionArea><wicri:noRegion>Norwich</wicri:noRegion></affiliation></author><author><name sortKey="Siffrin, Volker" sort="Siffrin, Volker" uniqKey="Siffrin V" first="Volker" last="Siffrin">Volker Siffrin</name><affiliation wicri:level="3"><nlm:aff id="A23">Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz</wicri:regionArea><placeName><region type="land" nuts="2">Rhénanie-Palatinat</region><settlement type="city">Mayence</settlement></placeName></affiliation></author><author><name sortKey="Slee, Mark" sort="Slee, Mark" uniqKey="Slee M" first="Mark" last="Slee">Mark Slee</name><affiliation wicri:level="1"><nlm:aff id="A113">Department of Neurology, Flinders University, Adelaide, South Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Neurology, Flinders University, Adelaide, South Australia</wicri:regionArea><wicri:noRegion>South Australia</wicri:noRegion></affiliation></author><author><name sortKey="Sorensen, Per Soelberg" sort="Sorensen, Per Soelberg" uniqKey="Sorensen P" first="Per Soelberg" last="Sorensen">Per Soelberg Sorensen</name><affiliation wicri:level="3"><nlm:aff id="A16">Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Neurology, Danish Multiple Sclerosis Center, Copenhagen University Hospital, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Sorosina, Melissa" sort="Sorosina, Melissa" uniqKey="Sorosina M" first="Melissa" last="Sorosina">Melissa Sorosina</name><affiliation wicri:level="3"><nlm:aff id="A25">Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Genetics of Neurological complex disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Sospedra, Mireia" sort="Sospedra, Mireia" uniqKey="Sospedra M" first="Mireia" last="Sospedra">Mireia Sospedra</name><affiliation wicri:level="3"><nlm:aff id="A76">Institute for Neuroimmunology and Clinical MS Research (inims), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Neuroimmunology and Clinical MS Research (inims), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A77">Department of Neuroimmunology and MS Research, Neurology Clinic, University Hospital Zürich, Zürich, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Neuroimmunology and MS Research, Neurology Clinic, University Hospital Zürich, Zürich</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName></affiliation></author><author><name sortKey="Spurkland, Anne" sort="Spurkland, Anne" uniqKey="Spurkland A" first="Anne" last="Spurkland">Anne Spurkland</name><affiliation wicri:level="3"><nlm:aff id="A114">Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Institute of Basic Medical Sciences, University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Strange, Amy" sort="Strange, Amy" uniqKey="Strange A" first="Amy" last="Strange">Amy Strange</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Sundqvist, Emilie" sort="Sundqvist, Emilie" uniqKey="Sundqvist E" first="Emilie" last="Sundqvist">Emilie Sundqvist</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Thijs, Vincent" sort="Thijs, Vincent" uniqKey="Thijs V" first="Vincent" last="Thijs">Vincent Thijs</name><affiliation wicri:level="1"><nlm:aff id="A105">Laboratory of Neurobiology, Vesalius Research Center, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Laboratory of Neurobiology, Vesalius Research Center, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A106">Experimental Neurology, Leuven Research Institute for Neurodegenerative Diseases (LIND), University of Leuven (KU Leuven), Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Experimental Neurology, Leuven Research Institute for Neurodegenerative Diseases (LIND), University of Leuven (KU Leuven), Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A107">Department of Neurology, University Hospitals Leuven, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Neurology, University Hospitals Leuven, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Thorpe, John" sort="Thorpe, John" uniqKey="Thorpe J" first="John" last="Thorpe">John Thorpe</name><affiliation wicri:level="1"><nlm:aff id="A115">Department of Neurology, Peterborough City Hospital, Peterborough, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurology, Peterborough City Hospital, Peterborough</wicri:regionArea><wicri:noRegion>Peterborough</wicri:noRegion></affiliation></author><author><name sortKey="Ticca, Anna" sort="Ticca, Anna" uniqKey="Ticca A" first="Anna" last="Ticca">Anna Ticca</name><affiliation wicri:level="1"><nlm:aff id="A116">Neurology and Stroke Unit, San Francesco Hospital, Nuoro, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Neurology and Stroke Unit, San Francesco Hospital, Nuoro</wicri:regionArea><wicri:noRegion>Nuoro</wicri:noRegion></affiliation></author><author><name sortKey="Tienari, Pentti" sort="Tienari, Pentti" uniqKey="Tienari P" first="Pentti" last="Tienari">Pentti Tienari</name><affiliation wicri:level="1"><nlm:aff id="A117">Department of Neurology, Helsinki University Central Hospital and Molecular Neurology Programme, Biomedicum, University of Helsinki, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Neurology, Helsinki University Central Hospital and Molecular Neurology Programme, Biomedicum, University of Helsinki, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Van Duijn, Cornelia" sort="Van Duijn, Cornelia" uniqKey="Van Duijn C" first="Cornelia" last="Van Duijn">Cornelia Van Duijn</name><affiliation wicri:level="3"><nlm:aff id="A118">Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Visser, Elizabeth M" sort="Visser, Elizabeth M" uniqKey="Visser E" first="Elizabeth M" last="Visser">Elizabeth M. Visser</name><affiliation wicri:level="1"><nlm:aff id="A119">Division of Applied Health Sciences, University of Aberdeen, Foresterhill, Aberdeen, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Applied Health Sciences, University of Aberdeen, Foresterhill, Aberdeen</wicri:regionArea><wicri:noRegion>Aberdeen</wicri:noRegion></affiliation></author><author><name sortKey="Vucic, Steve" sort="Vucic, Steve" uniqKey="Vucic S" first="Steve" last="Vucic">Steve Vucic</name><affiliation wicri:level="4"><nlm:aff id="A14">Westmead Millennium Institute, University of Sydney, New South Wales, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Westmead Millennium Institute, University of Sydney, New South Wales</wicri:regionArea><orgName type="university">Université de Sydney</orgName><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Westerlind, Helga" sort="Westerlind, Helga" uniqKey="Westerlind H" first="Helga" last="Westerlind">Helga Westerlind</name><affiliation wicri:level="3"><nlm:aff id="A30">Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Neuroscience, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Wiley, James S" sort="Wiley, James S" uniqKey="Wiley J" first="James S" last="Wiley">James S. Wiley</name><affiliation wicri:level="4"><nlm:aff id="A58">Florey Institute of Neuroscience and Mental Health, University of Melbourne, Victoria, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Florey Institute of Neuroscience and Mental Health, University of Melbourne, Victoria</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Wilkins, Alastair" sort="Wilkins, Alastair" uniqKey="Wilkins A" first="Alastair" last="Wilkins">Alastair Wilkins</name><affiliation wicri:level="1"><nlm:aff id="A120">Institute of Clinical Neurosciences, University of Bristol, Frenchay Hospital, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Clinical Neurosciences, University of Bristol, Frenchay Hospital, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><affiliation wicri:level="4"><nlm:aff id="A121">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Winkelmann, Juliane" sort="Winkelmann, Juliane" uniqKey="Winkelmann J" first="Juliane" last="Winkelmann">Juliane Winkelmann</name><affiliation wicri:level="4"><nlm:aff id="A19">Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A20">Munich Cluster for Systems Neurology (SyNergy), Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Munich Cluster for Systems Neurology (SyNergy), Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A122">Institut für Humangenetik, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Humangenetik, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A123">Institut für Humangenetik, Helmholtz Zentrum München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Humangenetik, Helmholtz Zentrum München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Zajicek, John" sort="Zajicek, John" uniqKey="Zajicek J" first="John" last="Zajicek">John Zajicek</name><affiliation wicri:level="1"><nlm:aff id="A75">Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth</wicri:regionArea><wicri:noRegion>Plymouth</wicri:noRegion></affiliation></author><author><name sortKey="Zindler, Eva" sort="Zindler, Eva" uniqKey="Zindler E" first="Eva" last="Zindler">Eva Zindler</name><affiliation wicri:level="3"><nlm:aff id="A23">Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), Johannes Gutenberg University-Medical Center, Mainz</wicri:regionArea><placeName><region type="land" nuts="2">Rhénanie-Palatinat</region><settlement type="city">Mayence</settlement></placeName></affiliation></author><author><name sortKey="Haines, Jonathan L" sort="Haines, Jonathan L" uniqKey="Haines J" first="Jonathan L" last="Haines">Jonathan L. Haines</name><affiliation wicri:level="2"><nlm:aff id="A8">Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Pericak Vance, Margaret A" sort="Pericak Vance, Margaret A" uniqKey="Pericak Vance M" first="Margaret A" last="Pericak-Vance">Margaret A. Pericak-Vance</name><affiliation wicri:level="2"><nlm:aff id="A1">John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Ivinson, Adrian J" sort="Ivinson, Adrian J" uniqKey="Ivinson A" first="Adrian J" last="Ivinson">Adrian J. Ivinson</name><affiliation wicri:level="2"><nlm:aff id="A124">Harvard NeuroDiscovery Center, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard NeuroDiscovery Center, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Stewart, Graeme" sort="Stewart, Graeme" uniqKey="Stewart G" first="Graeme" last="Stewart">Graeme Stewart</name><affiliation wicri:level="4"><nlm:aff id="A14">Westmead Millennium Institute, University of Sydney, New South Wales, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Westmead Millennium Institute, University of Sydney, New South Wales</wicri:regionArea><orgName type="university">Université de Sydney</orgName><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Hafler, David" sort="Hafler, David" uniqKey="Hafler D" first="David" last="Hafler">David Hafler</name><affiliation wicri:level="2"><nlm:aff id="A10">Program in Medical and Population Genetics, Broad Institute of Harvard University and MIT, Cambridge, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard University and MIT, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A11">Department of Neurology, Yale University School of Medicine, New Haven, Connecticut, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Yale University School of Medicine, New Haven, Connecticut</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A125">Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation></author><author><name sortKey="Hauser, Stephen L" sort="Hauser, Stephen L" uniqKey="Hauser S" first="Stephen L" last="Hauser">Stephen L. Hauser</name><affiliation wicri:level="2"><nlm:aff id="A31">Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of California at San Francisco, Sandler Neurosciences Center, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Compston, Alastair" sort="Compston, Alastair" uniqKey="Compston A" first="Alastair" last="Compston">Alastair Compston</name><affiliation wicri:level="4"><nlm:aff id="A9">Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Mcvean, Gil" sort="Mcvean, Gil" uniqKey="Mcvean G" first="Gil" last="Mcvean">Gil Mcvean</name><affiliation wicri:level="4"><nlm:aff id="A7">The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="De Jager, Philip" sort="De Jager, Philip" uniqKey="De Jager P" first="Philip" last="De Jager">Philip De Jager</name><affiliation wicri:level="2"><nlm:aff id="A2">Department of Neurology, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Brigham & Women’s Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Brigham & Women’s Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A5">Harvard Medical School, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A10">Program in Medical and Population Genetics, Broad Institute of Harvard University and MIT, Cambridge, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard University and MIT, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Sawcer, Stephen" sort="Sawcer, Stephen" uniqKey="Sawcer S" first="Stephen" last="Sawcer">Stephen Sawcer</name><affiliation wicri:level="4"><nlm:aff id="A9">Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Mccauley, Jacob L" sort="Mccauley, Jacob L" uniqKey="Mccauley J" first="Jacob L" last="Mccauley">Jacob L. Mccauley</name><affiliation wicri:level="2"><nlm:aff id="A1">John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author></analytic><series><title level="j">Nature genetics</title><idno type="ISSN">1061-4036</idno><idno type="eISSN">1546-1718</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Using the ImmunoChip custom genotyping array, we analysed 14,498 multiple sclerosis subjects and 24,091 healthy controls for 161,311 autosomal variants and identified 135 potentially associated regions (p-value < 1.0 × 10<sup>-4</sup>). In a replication phase, we combined these data with previous genome-wide association study (GWAS) data from an independent 14,802 multiple sclerosis subjects and 26,703 healthy controls. In these 80,094 individuals of European ancestry we identified 48 new susceptibility variants (p-value < 5.0 × 10<sup>-8</sup>); three found after conditioning on previously identified variants. Thus, there are now 110 established multiple sclerosis risk variants in 103 discrete loci outside of the Major Histocompatibility Complex. With high resolution Bayesian fine-mapping, we identified five regions where one variant accounted for more than 50% of the posterior probability of association. 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Londres</li><li>Hambourg</li><li>Hollande-Méridionale</li><li>Hovedstaden</li><li>Languedoc-Roussillon</li><li>Latium</li><li>Lombardie</li><li>Massachusetts</li><li>Midlands de l'Ouest</li><li>Nouvelle-Aquitaine</li><li>Nouvelle-Galles du Sud</li><li>Occitanie (région administrative)</li><li>Oxfordshire</li><li>Pennsylvanie</li><li>Piémont</li><li>Québec</li><li>Rhénanie-Palatinat</li><li>Région Bretagne</li><li>Région Normandie</li><li>Schleswig-Holstein</li><li>Svealand</li><li>Tennessee</li><li>Uusimaa</li><li>Victoria (État)</li><li>Écosse</li><li>Île-de-France</li><li>Østlandet</li></region><settlement><li>Berlin</li><li>Birmingham</li><li>Bobigny</li><li>Bordeaux</li><li>Caen</li><li>Cambridge</li><li>Copenhague</li><li>Hambourg</li><li>Helsinki</li><li>Kiel</li><li>Londres</li><li>Mayence</li><li>Melbourne</li><li>Milan</li><li>Montpellier</li><li>Montréal</li><li>Munich</li><li>Oslo</li><li>Oxford</li><li>Paris</li><li>Rennes</li><li>Rome</li><li>Rotterdam</li><li>Stockholm</li><li>Sydney</li><li>Turin</li><li>Zurich</li><li>Édimbourg</li><li>Évry (Essonne)</li></settlement><orgName><li>University College de Londres</li><li>Université d'Helsinki</li><li>Université d'Oxford</li><li>Université d'Édimbourg</li><li>Université de Cambridge</li><li>Université de Melbourne</li><li>Université de Sydney</li><li>Université technique de Munich</li></orgName></list><tree><country name="États-Unis"><region name="Floride"><name sortKey="Beecham, Ashley H" sort="Beecham, Ashley H" uniqKey="Beecham A" first="Ashley H" last="Beecham">Ashley H. Beecham</name></region><name sortKey="Baranzini, Sergio E" sort="Baranzini, Sergio E" uniqKey="Baranzini S" first="Sergio E" last="Baranzini">Sergio E. Baranzini</name><name sortKey="Barcellos, Lisa F" sort="Barcellos, Lisa F" uniqKey="Barcellos L" first="Lisa F" last="Barcellos">Lisa F. Barcellos</name><name sortKey="Barcellos, Lisa F" sort="Barcellos, Lisa F" uniqKey="Barcellos L" first="Lisa F" last="Barcellos">Lisa F. Barcellos</name><name sortKey="Barcellos, Lisa F" sort="Barcellos, Lisa F" uniqKey="Barcellos L" first="Lisa F" last="Barcellos">Lisa F. Barcellos</name><name sortKey="Caillier, Stacy J" sort="Caillier, Stacy J" uniqKey="Caillier S" first="Stacy J" last="Caillier">Stacy J. Caillier</name><name sortKey="Cotsapas, Chris" sort="Cotsapas, Chris" uniqKey="Cotsapas C" first="Chris" last="Cotsapas">Chris Cotsapas</name><name sortKey="Cotsapas, Chris" sort="Cotsapas, Chris" uniqKey="Cotsapas C" first="Chris" last="Cotsapas">Chris Cotsapas</name><name sortKey="Cotsapas, Chris" sort="Cotsapas, Chris" uniqKey="Cotsapas C" first="Chris" last="Cotsapas">Chris Cotsapas</name><name sortKey="Cree, Bruce A C" sort="Cree, Bruce A C" uniqKey="Cree B" first="Bruce A C" last="Cree">Bruce A C. Cree</name><name sortKey="Davis, Mary F" sort="Davis, Mary F" uniqKey="Davis M" first="Mary F" last="Davis">Mary F. Davis</name><name sortKey="De Jager, Philip" sort="De Jager, Philip" uniqKey="De Jager P" first="Philip" last="De Jager">Philip De Jager</name><name sortKey="De Jager, Philip" sort="De Jager, Philip" uniqKey="De Jager P" first="Philip" last="De Jager">Philip De Jager</name><name sortKey="De Jager, Philip" sort="De Jager, Philip" uniqKey="De Jager P" first="Philip" last="De Jager">Philip De Jager</name><name sortKey="Delgado, Silvia R" sort="Delgado, Silvia R" uniqKey="Delgado S" first="Silvia R" last="Delgado">Silvia R. Delgado</name><name sortKey="Frohlich, Irene Y" sort="Frohlich, Irene Y" uniqKey="Frohlich I" first="Irene Y" last="Frohlich">Irene Y. Frohlich</name><name sortKey="Gourraud, Pierre Antoine" sort="Gourraud, Pierre Antoine" uniqKey="Gourraud P" first="Pierre-Antoine" last="Gourraud">Pierre-Antoine Gourraud</name><name sortKey="Hadjixenofontos, Athena" sort="Hadjixenofontos, Athena" uniqKey="Hadjixenofontos A" first="Athena" last="Hadjixenofontos">Athena Hadjixenofontos</name><name sortKey="Hafler, David" sort="Hafler, David" uniqKey="Hafler D" first="David" last="Hafler">David Hafler</name><name sortKey="Hafler, David" sort="Hafler, David" uniqKey="Hafler D" first="David" last="Hafler">David Hafler</name><name sortKey="Hafler, David" sort="Hafler, David" uniqKey="Hafler D" first="David" last="Hafler">David Hafler</name><name sortKey="Haines, Jonathan L" sort="Haines, Jonathan L" uniqKey="Haines J" first="Jonathan L" last="Haines">Jonathan L. Haines</name><name sortKey="Hakonarson, Hakon" sort="Hakonarson, Hakon" uniqKey="Hakonarson H" first="Hakon" last="Hakonarson">Hakon Hakonarson</name><name sortKey="Hakonarson, Hakon" sort="Hakonarson, Hakon" uniqKey="Hakonarson H" first="Hakon" last="Hakonarson">Hakon Hakonarson</name><name sortKey="Hauser, Stephen L" sort="Hauser, Stephen L" uniqKey="Hauser S" first="Stephen L" last="Hauser">Stephen L. Hauser</name><name sortKey="Ivinson, Adrian J" sort="Ivinson, Adrian J" uniqKey="Ivinson A" first="Adrian J" last="Ivinson">Adrian J. Ivinson</name><name sortKey="Konidari, Ioanna" sort="Konidari, Ioanna" uniqKey="Konidari I" first="Ioanna" last="Konidari">Ioanna Konidari</name><name sortKey="Lee, Michelle H" sort="Lee, Michelle H" uniqKey="Lee M" first="Michelle H" last="Lee">Michelle H. Lee</name><name sortKey="Macciardi, Fabio" sort="Macciardi, Fabio" uniqKey="Macciardi F" first="Fabio" last="Macciardi">Fabio Macciardi</name><name sortKey="Manrique, Clara P" sort="Manrique, Clara P" uniqKey="Manrique C" first="Clara P" last="Manrique">Clara P. Manrique</name><name sortKey="Mccabe, Cristin" sort="Mccabe, Cristin" uniqKey="Mccabe C" first="Cristin" last="Mccabe">Cristin Mccabe</name><name sortKey="Mccauley, Jacob L" sort="Mccauley, Jacob L" uniqKey="Mccauley J" first="Jacob L" last="Mccauley">Jacob L. Mccauley</name><name sortKey="Oksenberg, Jorge R" sort="Oksenberg, Jorge R" uniqKey="Oksenberg J" first="Jorge R" last="Oksenberg">Jorge R. Oksenberg</name><name sortKey="Patsopoulos, Nikolaos A" sort="Patsopoulos, Nikolaos A" uniqKey="Patsopoulos N" first="Nikolaos A" last="Patsopoulos">Nikolaos A. Patsopoulos</name><name sortKey="Patsopoulos, Nikolaos A" sort="Patsopoulos, Nikolaos A" uniqKey="Patsopoulos N" first="Nikolaos A" last="Patsopoulos">Nikolaos A. Patsopoulos</name><name sortKey="Patsopoulos, Nikolaos A" sort="Patsopoulos, Nikolaos A" uniqKey="Patsopoulos N" first="Nikolaos A" last="Patsopoulos">Nikolaos A. Patsopoulos</name><name sortKey="Patsopoulos, Nikolaos A" sort="Patsopoulos, Nikolaos A" uniqKey="Patsopoulos N" first="Nikolaos A" last="Patsopoulos">Nikolaos A. Patsopoulos</name><name sortKey="Patsopoulos, Nikolaos A" sort="Patsopoulos, Nikolaos A" uniqKey="Patsopoulos N" first="Nikolaos A" last="Patsopoulos">Nikolaos A. Patsopoulos</name><name sortKey="Pericak Vance, Margaret A" sort="Pericak Vance, Margaret A" uniqKey="Pericak Vance M" first="Margaret A" last="Pericak-Vance">Margaret A. Pericak-Vance</name><name sortKey="Quach, Hong" sort="Quach, Hong" uniqKey="Quach H" first="Hong" last="Quach">Hong Quach</name><name sortKey="Schaefer, Catherine" sort="Schaefer, Catherine" uniqKey="Schaefer C" first="Catherine" last="Schaefer">Catherine Schaefer</name><name sortKey="Schnetz Boutaud, Nathalie C" sort="Schnetz Boutaud, Nathalie C" uniqKey="Schnetz Boutaud N" first="Nathalie C" last="Schnetz-Boutaud">Nathalie C. Schnetz-Boutaud</name><name sortKey="Shen, Ling" sort="Shen, Ling" uniqKey="Shen L" first="Ling" last="Shen">Ling Shen</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Xifara, Dionysia K" sort="Xifara, Dionysia K" uniqKey="Xifara D" first="Dionysia K" last="Xifara">Dionysia K. Xifara</name></region><name sortKey="Anderson, Carl" sort="Anderson, Carl" uniqKey="Anderson C" first="Carl" last="Anderson">Carl Anderson</name><name sortKey="Andrews, Robert" sort="Andrews, Robert" uniqKey="Andrews R" first="Robert" last="Andrews">Robert Andrews</name><name sortKey="Baker, Amie" sort="Baker, Amie" uniqKey="Baker A" first="Amie" last="Baker">Amie Baker</name><name sortKey="Ban, Maria" sort="Ban, Maria" uniqKey="Ban M" first="Maria" last="Ban">Maria Ban</name><name sortKey="Band, Gavin" sort="Band, Gavin" uniqKey="Band G" first="Gavin" last="Band">Gavin Band</name><name sortKey="Barrett, Jeffrey" sort="Barrett, Jeffrey" uniqKey="Barrett J" first="Jeffrey" last="Barrett">Jeffrey Barrett</name><name sortKey="Bellenguez, Celine" sort="Bellenguez, Celine" uniqKey="Bellenguez C" first="Céline" last="Bellenguez">Céline Bellenguez</name><name sortKey="Bernardinelli, Luisa" sort="Bernardinelli, Luisa" uniqKey="Bernardinelli L" first="Luisa" last="Bernardinelli">Luisa Bernardinelli</name><name sortKey="Blackburn, Hannah" sort="Blackburn, Hannah" uniqKey="Blackburn H" first="Hannah" last="Blackburn">Hannah Blackburn</name><name sortKey="Compston, Alastair" sort="Compston, Alastair" uniqKey="Compston A" first="Alastair" last="Compston">Alastair Compston</name><name sortKey="Deloukas, Panos" sort="Deloukas, Panos" uniqKey="Deloukas P" first="Panos" last="Deloukas">Panos Deloukas</name><name sortKey="Dilthey, Alexander T" sort="Dilthey, Alexander T" uniqKey="Dilthey A" first="Alexander T" last="Dilthey">Alexander T. Dilthey</name><name sortKey="Donnelly, Peter" sort="Donnelly, Peter" uniqKey="Donnelly P" first="Peter" last="Donnelly">Peter Donnelly</name><name sortKey="Duddy, Martin" sort="Duddy, Martin" uniqKey="Duddy M" first="Martin" last="Duddy">Martin Duddy</name><name sortKey="Edkins, Sarah" sort="Edkins, Sarah" uniqKey="Edkins S" first="Sarah" last="Edkins">Sarah Edkins</name><name sortKey="Evangelou, Nikos" sort="Evangelou, Nikos" uniqKey="Evangelou N" first="Nikos" last="Evangelou">Nikos Evangelou</name><name sortKey="Fiddes, Barnaby" sort="Fiddes, Barnaby" uniqKey="Fiddes B" first="Barnaby" last="Fiddes">Barnaby Fiddes</name><name sortKey="Freeman, Colin" sort="Freeman, Colin" uniqKey="Freeman C" first="Colin" last="Freeman">Colin Freeman</name><name sortKey="Graham, Andrew" sort="Graham, Andrew" uniqKey="Graham A" first="Andrew" last="Graham">Andrew Graham</name><name sortKey="Halfpenny, Christopher" sort="Halfpenny, Christopher" uniqKey="Halfpenny C" first="Christopher" last="Halfpenny">Christopher Halfpenny</name><name sortKey="Hall, Gillian" sort="Hall, Gillian" uniqKey="Hall G" first="Gillian" last="Hall">Gillian Hall</name><name sortKey="Harley, James" sort="Harley, James" uniqKey="Harley J" first="James" last="Harley">James Harley</name><name sortKey="Harrower, Timothy" sort="Harrower, Timothy" uniqKey="Harrower T" first="Timothy" last="Harrower">Timothy Harrower</name><name sortKey="Hawkins, Clive" sort="Hawkins, Clive" uniqKey="Hawkins C" first="Clive" last="Hawkins">Clive Hawkins</name><name sortKey="Hellenthal, Garrett" sort="Hellenthal, Garrett" uniqKey="Hellenthal G" first="Garrett" last="Hellenthal">Garrett Hellenthal</name><name sortKey="Hillier, Charles" sort="Hillier, Charles" uniqKey="Hillier C" first="Charles" last="Hillier">Charles Hillier</name><name sortKey="Hobart, Jeremy" sort="Hobart, Jeremy" uniqKey="Hobart J" first="Jeremy" last="Hobart">Jeremy Hobart</name><name sortKey="Hunt, Sarah E" sort="Hunt, Sarah E" uniqKey="Hunt S" first="Sarah E" last="Hunt">Sarah E. Hunt</name><name sortKey="Kemppinen, Anu" sort="Kemppinen, Anu" uniqKey="Kemppinen A" first="Anu" last="Kemppinen">Anu Kemppinen</name><name sortKey="Kendall, Brian" sort="Kendall, Brian" uniqKey="Kendall B" first="Brian" last="Kendall">Brian Kendall</name><name sortKey="Langford, Cordelia" sort="Langford, Cordelia" uniqKey="Langford C" first="Cordelia" last="Langford">Cordelia Langford</name><name sortKey="Mazibrada, Gordon" sort="Mazibrada, Gordon" uniqKey="Mazibrada G" first="Gordon" last="Mazibrada">Gordon Mazibrada</name><name sortKey="Mcvean, Gil" sort="Mcvean, Gil" uniqKey="Mcvean G" first="Gil" last="Mcvean">Gil Mcvean</name><name sortKey="Moutsianas, Loukas" sort="Moutsianas, Loukas" uniqKey="Moutsianas L" first="Loukas" last="Moutsianas">Loukas Moutsianas</name><name sortKey="Nicholas, Richard" sort="Nicholas, Richard" uniqKey="Nicholas R" first="Richard" last="Nicholas">Richard Nicholas</name><name sortKey="Pirinen, Matti" sort="Pirinen, Matti" uniqKey="Pirinen M" first="Matti" last="Pirinen">Matti Pirinen</name><name sortKey="Price, Sian E" sort="Price, Sian E" uniqKey="Price S" first="Siân E" last="Price">Siân E. 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Wiley</name></country><country name="Belgique"><noRegion><name sortKey="Goris, An" sort="Goris, An" uniqKey="Goris A" first="An" last="Goris">An Goris</name></noRegion><name sortKey="Cosemans, Leentje" sort="Cosemans, Leentje" uniqKey="Cosemans L" first="Leentje" last="Cosemans">Leentje Cosemans</name><name sortKey="Dubois, Benedicte" sort="Dubois, Benedicte" uniqKey="Dubois B" first="Bénédicte" last="Dubois">Bénédicte Dubois</name><name sortKey="Nagels, Guy" sort="Nagels, Guy" uniqKey="Nagels G" first="Guy" last="Nagels">Guy Nagels</name><name sortKey="Robberecht, Wim" sort="Robberecht, Wim" uniqKey="Robberecht W" first="Wim" last="Robberecht">Wim Robberecht</name><name sortKey="Robberecht, Wim" sort="Robberecht, Wim" uniqKey="Robberecht W" first="Wim" last="Robberecht">Wim Robberecht</name><name sortKey="Robberecht, Wim" sort="Robberecht, Wim" uniqKey="Robberecht W" first="Wim" last="Robberecht">Wim Robberecht</name><name sortKey="Thijs, Vincent" sort="Thijs, Vincent" uniqKey="Thijs 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name="Uusimaa"><name sortKey="Saarela, Janna" sort="Saarela, Janna" uniqKey="Saarela J" first="Janna" last="Saarela">Janna Saarela</name></region><name sortKey="Elovaara, Irina" sort="Elovaara, Irina" uniqKey="Elovaara I" first="Irina" last="Elovaara">Irina Elovaara</name><name sortKey="Koivisto, Keijo" sort="Koivisto, Keijo" uniqKey="Koivisto K" first="Keijo" last="Koivisto">Keijo Koivisto</name><name sortKey="Lepp, Virpi" sort="Lepp, Virpi" uniqKey="Lepp V" first="Virpi" last="Lepp">Virpi Lepp</name><name sortKey="M Nnisto, Satu" sort="M Nnisto, Satu" uniqKey="M Nnisto S" first="Satu" last="M Nnistö">Satu M Nnistö</name><name sortKey="Reunanen, Mauri" sort="Reunanen, Mauri" uniqKey="Reunanen M" first="Mauri" last="Reunanen">Mauri Reunanen</name><name sortKey="Reunanen, Mauri" sort="Reunanen, Mauri" uniqKey="Reunanen M" first="Mauri" last="Reunanen">Mauri Reunanen</name><name sortKey="Tienari, Pentti" sort="Tienari, Pentti" uniqKey="Tienari P" first="Pentti" last="Tienari">Pentti Tienari</name></country><country name="France"><region name="Île-de-France"><name sortKey="Fontaine, Bertrand" sort="Fontaine, Bertrand" uniqKey="Fontaine B" first="Bertrand" last="Fontaine">Bertrand Fontaine</name></region><name sortKey="Alizadeh, Mehdi" sort="Alizadeh, Mehdi" uniqKey="Alizadeh M" first="Mehdi" last="Alizadeh">Mehdi Alizadeh</name><name sortKey="Brochet, Bruno" sort="Brochet, Bruno" uniqKey="Brochet B" first="Bruno" last="Brochet">Bruno Brochet</name><name sortKey="Camu, William" sort="Camu, William" uniqKey="Camu W" first="William" last="Camu">William Camu</name><name sortKey="Carpentier, Wassila" sort="Carpentier, Wassila" uniqKey="Carpentier W" first="Wassila" last="Carpentier">Wassila Carpentier</name><name sortKey="Coman, Irene" sort="Coman, Irene" uniqKey="Coman I" first="Irène" last="Coman">Irène Coman</name><name sortKey="Cournu Rebeix, Isabelle" sort="Cournu Rebeix, Isabelle" uniqKey="Cournu Rebeix I" first="Isabelle" last="Cournu-Rebeix">Isabelle Cournu-Rebeix</name><name sortKey="Damotte, Vincent" sort="Damotte, Vincent" uniqKey="Damotte V" first="Vincent" last="Damotte">Vincent Damotte</name><name sortKey="Defer, Gilles" sort="Defer, Gilles" uniqKey="Defer G" first="Gilles" last="Defer">Gilles Defer</name><name sortKey="Lathrop, Mark" sort="Lathrop, Mark" uniqKey="Lathrop M" first="Mark" last="Lathrop">Mark Lathrop</name><name sortKey="Lathrop, Mark" sort="Lathrop, Mark" uniqKey="Lathrop M" first="Mark" last="Lathrop">Mark Lathrop</name><name sortKey="Lebrun Frenay, Christine" sort="Lebrun Frenay, Christine" uniqKey="Lebrun Frenay C" first="Christine" last="Lebrun-Frenay">Christine Lebrun-Frenay</name></country><country name="Allemagne"><region name="Bavière"><name sortKey="Hemmer, Bernhard" sort="Hemmer, Bernhard" uniqKey="Hemmer B" first="Bernhard" last="Hemmer">Bernhard Hemmer</name></region><name sortKey="Berthele, Achim" sort="Berthele, Achim" uniqKey="Berthele A" first="Achim" last="Berthele">Achim Berthele</name><name sortKey="Biberacher, Viola" sort="Biberacher, Viola" uniqKey="Biberacher V" first="Viola" last="Biberacher">Viola Biberacher</name><name sortKey="Binder, Thomas M C" sort="Binder, Thomas M C" uniqKey="Binder T" first="Thomas M C" last="Binder">Thomas M C. Binder</name><name sortKey="Buck, Dorothea" sort="Buck, Dorothea" uniqKey="Buck D" first="Dorothea" last="Buck">Dorothea Buck</name><name sortKey="Franke, Andre" sort="Franke, Andre" uniqKey="Franke A" first="Andre" last="Franke">Andre Franke</name><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><name sortKey="Graetz, Christiane" sort="Graetz, Christiane" uniqKey="Graetz C" first="Christiane" last="Graetz">Christiane Graetz</name><name sortKey="Grummel, Verena" sort="Grummel, Verena" uniqKey="Grummel V" first="Verena" last="Grummel">Verena Grummel</name><name sortKey="Hemmer, Bernhard" sort="Hemmer, Bernhard" uniqKey="Hemmer B" first="Bernhard" last="Hemmer">Bernhard Hemmer</name><name sortKey="Hemmer, Bernhard" sort="Hemmer, Bernhard" uniqKey="Hemmer B" first="Bernhard" last="Hemmer">Bernhard Hemmer</name><name sortKey="Hoshi, Muni" sort="Hoshi, Muni" uniqKey="Hoshi M" first="Muni" last="Hoshi">Muni Hoshi</name><name sortKey="Jel I, Ilijas" sort="Jel I, Ilijas" uniqKey="Jel I I" first="Ilijas" last="Jel I">Ilijas Jel I</name><name sortKey="Jochim, Angela" sort="Jochim, Angela" uniqKey="Jochim A" first="Angela" last="Jochim">Angela Jochim</name><name sortKey="Korn, Thomas" sort="Korn, Thomas" uniqKey="Korn T" first="Thomas" last="Korn">Thomas Korn</name><name sortKey="Kronsbein, Helena" sort="Kronsbein, Helena" uniqKey="Kronsbein H" first="Helena" last="Kronsbein">Helena Kronsbein</name><name sortKey="Lill, Christina M" sort="Lill, Christina M" uniqKey="Lill C" first="Christina M" last="Lill">Christina M. Lill</name><name sortKey="Lill, Christina M" sort="Lill, Christina M" uniqKey="Lill C" first="Christina M" last="Lill">Christina M. Lill</name><name sortKey="Luessi, Felix" sort="Luessi, Felix" uniqKey="Luessi F" first="Felix" last="Luessi">Felix Luessi</name><name sortKey="Martin, Roland" sort="Martin, Roland" uniqKey="Martin R" first="Roland" last="Martin">Roland Martin</name><name sortKey="Selter, Rebecca C" sort="Selter, Rebecca C" uniqKey="Selter R" first="Rebecca C" last="Selter">Rebecca C. Selter</name><name sortKey="Siffrin, Volker" sort="Siffrin, Volker" uniqKey="Siffrin V" first="Volker" last="Siffrin">Volker Siffrin</name><name sortKey="Sospedra, Mireia" sort="Sospedra, Mireia" uniqKey="Sospedra M" first="Mireia" last="Sospedra">Mireia Sospedra</name><name sortKey="Winkelmann, Juliane" sort="Winkelmann, Juliane" uniqKey="Winkelmann J" first="Juliane" last="Winkelmann">Juliane Winkelmann</name><name sortKey="Winkelmann, Juliane" sort="Winkelmann, Juliane" uniqKey="Winkelmann J" first="Juliane" last="Winkelmann">Juliane Winkelmann</name><name sortKey="Winkelmann, Juliane" sort="Winkelmann, Juliane" uniqKey="Winkelmann J" first="Juliane" last="Winkelmann">Juliane Winkelmann</name><name sortKey="Winkelmann, Juliane" sort="Winkelmann, Juliane" uniqKey="Winkelmann J" first="Juliane" last="Winkelmann">Juliane Winkelmann</name><name sortKey="Zindler, Eva" sort="Zindler, Eva" uniqKey="Zindler E" first="Eva" last="Zindler">Eva Zindler</name><name sortKey="Zipp, Frauke" sort="Zipp, Frauke" uniqKey="Zipp F" first="Frauke" last="Zipp">Frauke Zipp</name></country><country name="Suède"><region name="Svealand"><name sortKey="Martin, Claes" sort="Martin, Claes" uniqKey="Martin C" first="Claes" last="Martin">Claes Martin</name></region><name sortKey="Alfredsson, Lars" sort="Alfredsson, Lars" uniqKey="Alfredsson L" first="Lars" last="Alfredsson">Lars Alfredsson</name><name sortKey="Bomfim, Izaura L" sort="Bomfim, Izaura L" uniqKey="Bomfim I" first="Izaura L" last="Bomfim">Izaura L. Bomfim</name><name sortKey="Brundin, Lou" sort="Brundin, Lou" uniqKey="Brundin L" first="Lou" last="Brundin">Lou Brundin</name><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name><name sortKey="Hillert, Jan" sort="Hillert, Jan" uniqKey="Hillert J" first="Jan" last="Hillert">Jan Hillert</name><name sortKey="Jagodic, Maja" sort="Jagodic, Maja" uniqKey="Jagodic M" first="Maja" last="Jagodic">Maja Jagodic</name><name sortKey="Kockum, Ingrid" sort="Kockum, Ingrid" uniqKey="Kockum I" first="Ingrid" last="Kockum">Ingrid Kockum</name><name sortKey="Larsson, Malin" sort="Larsson, Malin" uniqKey="Larsson M" first="Malin" last="Larsson">Malin Larsson</name><name sortKey="Linden, Magdalena" sort="Linden, Magdalena" uniqKey="Linden M" first="Magdalena" last="Lindén">Magdalena Lindén</name><name sortKey="Link, Jenny" sort="Link, Jenny" uniqKey="Link J" first="Jenny" last="Link">Jenny Link</name><name sortKey="Lycke, Jan" sort="Lycke, Jan" uniqKey="Lycke J" first="Jan" last="Lycke">Jan Lycke</name><name sortKey="Nilsson, Petra" sort="Nilsson, Petra" uniqKey="Nilsson P" first="Petra" last="Nilsson">Petra Nilsson</name><name sortKey="Olsson, Tomas" sort="Olsson, Tomas" uniqKey="Olsson T" first="Tomas" last="Olsson">Tomas Olsson</name><name sortKey="Piehl, Fredrik" sort="Piehl, Fredrik" uniqKey="Piehl F" first="Fredrik" last="Piehl">Fredrik Piehl</name><name sortKey="Sundqvist, Emilie" sort="Sundqvist, Emilie" uniqKey="Sundqvist E" first="Emilie" last="Sundqvist">Emilie Sundqvist</name><name sortKey="Westerlind, Helga" sort="Westerlind, Helga" uniqKey="Westerlind H" first="Helga" last="Westerlind">Helga Westerlind</name></country><country name="Italie"><noRegion><name sortKey="D Lfonso, Sandra" sort="D Lfonso, Sandra" uniqKey="D Lfonso S" first="Sandra" last="D Lfonso">Sandra D Lfonso</name></noRegion><name sortKey="Agliardi, Cristina" sort="Agliardi, Cristina" uniqKey="Agliardi C" first="Cristina" last="Agliardi">Cristina Agliardi</name><name sortKey="Barizzone, Nadia" sort="Barizzone, Nadia" uniqKey="Barizzone N" first="Nadia" last="Barizzone">Nadia Barizzone</name><name sortKey="Bergamaschi, Laura" sort="Bergamaschi, Laura" uniqKey="Bergamaschi L" first="Laura" last="Bergamaschi">Laura Bergamaschi</name><name sortKey="Brambilla, Paola" sort="Brambilla, Paola" uniqKey="Brambilla P" first="Paola" last="Brambilla">Paola Brambilla</name><name sortKey="Cavalla, Paola" sort="Cavalla, Paola" uniqKey="Cavalla P" first="Paola" last="Cavalla">Paola Cavalla</name><name sortKey="Cavalla, Paola" sort="Cavalla, Paola" uniqKey="Cavalla P" first="Paola" last="Cavalla">Paola Cavalla</name><name sortKey="Comi, Giancarlo" sort="Comi, Giancarlo" uniqKey="Comi G" first="Giancarlo" last="Comi">Giancarlo Comi</name><name sortKey="Comi, Giancarlo" sort="Comi, Giancarlo" uniqKey="Comi G" first="Giancarlo" last="Comi">Giancarlo Comi</name><name sortKey="Corrado, Lucia" sort="Corrado, Lucia" uniqKey="Corrado L" first="Lucia" last="Corrado">Lucia Corrado</name><name sortKey="Cusi, Daniele" sort="Cusi, Daniele" uniqKey="Cusi D" first="Daniele" last="Cusi">Daniele Cusi</name><name sortKey="Di Sapio, Alessia" sort="Di Sapio, Alessia" uniqKey="Di Sapio A" first="Alessia" last="Di Sapio">Alessia Di Sapio</name><name sortKey="Esposito, Federica" sort="Esposito, Federica" uniqKey="Esposito F" first="Federica" last="Esposito">Federica Esposito</name><name sortKey="Esposito, Federica" sort="Esposito, Federica" uniqKey="Esposito F" first="Federica" last="Esposito">Federica Esposito</name><name sortKey="Galimberti, Daniela" sort="Galimberti, Daniela" uniqKey="Galimberti D" first="Daniela" last="Galimberti">Daniela Galimberti</name><name sortKey="Galimberti, Daniela" sort="Galimberti, Daniela" uniqKey="Galimberti D" first="Daniela" last="Galimberti">Daniela Galimberti</name><name sortKey="Guaschino, Clara" sort="Guaschino, Clara" uniqKey="Guaschino C" first="Clara" last="Guaschino">Clara Guaschino</name><name sortKey="Guaschino, Clara" sort="Guaschino, Clara" uniqKey="Guaschino C" first="Clara" last="Guaschino">Clara Guaschino</name><name sortKey="Leone, Maurizio A" sort="Leone, Maurizio A" uniqKey="Leone M" first="Maurizio A" last="Leone">Maurizio A. Leone</name><name sortKey="Liberatore, Giuseppe" sort="Liberatore, Giuseppe" uniqKey="Liberatore G" first="Giuseppe" last="Liberatore">Giuseppe Liberatore</name><name sortKey="Liberatore, Giuseppe" sort="Liberatore, Giuseppe" uniqKey="Liberatore G" first="Giuseppe" last="Liberatore">Giuseppe Liberatore</name><name sortKey="Macciardi, Fabio" sort="Macciardi, Fabio" uniqKey="Macciardi F" first="Fabio" last="Macciardi">Fabio Macciardi</name><name sortKey="Martinelli Boneschi, Filippo" sort="Martinelli Boneschi, Filippo" uniqKey="Martinelli Boneschi F" first="Filippo" last="Martinelli-Boneschi">Filippo Martinelli-Boneschi</name><name sortKey="Martinelli Boneschi, Filippo" sort="Martinelli Boneschi, Filippo" uniqKey="Martinelli Boneschi F" first="Filippo" last="Martinelli-Boneschi">Filippo Martinelli-Boneschi</name><name sortKey="Martinelli, Vittorio" sort="Martinelli, Vittorio" uniqKey="Martinelli V" first="Vittorio" last="Martinelli">Vittorio Martinelli</name><name sortKey="Rodegher, Mariaemma" sort="Rodegher, Mariaemma" uniqKey="Rodegher M" first="Mariaemma" last="Rodegher">Mariaemma Rodegher</name><name sortKey="Salvetti, Marco" sort="Salvetti, Marco" uniqKey="Salvetti M" first="Marco" last="Salvetti">Marco Salvetti</name><name sortKey="Sorosina, Melissa" sort="Sorosina, Melissa" uniqKey="Sorosina M" first="Melissa" last="Sorosina">Melissa Sorosina</name><name sortKey="Ticca, Anna" sort="Ticca, Anna" uniqKey="Ticca A" first="Anna" last="Ticca">Anna Ticca</name></country><country name="Norvège"><region name="Østlandet"><name sortKey="Harbo, Hanne F" sort="Harbo, Hanne F" uniqKey="Harbo H" first="Hanne F" last="Harbo">Hanne F. Harbo</name></region><name sortKey="Celius, Elisabeth G" sort="Celius, Elisabeth G" uniqKey="Celius E" first="Elisabeth G" last="Celius">Elisabeth G. Celius</name><name sortKey="Harbo, Hanne F" sort="Harbo, Hanne F" uniqKey="Harbo H" first="Hanne F" last="Harbo">Hanne F. Harbo</name><name sortKey="Lie, Benedicte A" sort="Lie, Benedicte A" uniqKey="Lie B" first="Benedicte A" last="Lie">Benedicte A. Lie</name><name sortKey="Lie, Benedicte A" sort="Lie, Benedicte A" uniqKey="Lie B" first="Benedicte A" last="Lie">Benedicte A. Lie</name><name sortKey="Mero, Inger Lise" sort="Mero, Inger Lise" uniqKey="Mero I" first="Inger-Lise" last="Mero">Inger-Lise Mero</name><name sortKey="Mero, Inger Lise" sort="Mero, Inger Lise" uniqKey="Mero I" first="Inger-Lise" last="Mero">Inger-Lise Mero</name><name sortKey="Mero, Inger Lise" sort="Mero, Inger Lise" uniqKey="Mero I" first="Inger-Lise" last="Mero">Inger-Lise Mero</name><name sortKey="Myhr, Kjell Morten" sort="Myhr, Kjell Morten" uniqKey="Myhr K" first="Kjell-Morten" last="Myhr">Kjell-Morten Myhr</name><name sortKey="Spurkland, Anne" sort="Spurkland, Anne" uniqKey="Spurkland A" first="Anne" last="Spurkland">Anne Spurkland</name></country><country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="Hintzen, Rogier" sort="Hintzen, Rogier" uniqKey="Hintzen R" first="Rogier" last="Hintzen">Rogier Hintzen</name></region><name sortKey="Mescheriakova, Julia" sort="Mescheriakova, Julia" uniqKey="Mescheriakova J" first="Julia" last="Mescheriakova">Julia Mescheriakova</name><name sortKey="Van Duijn, Cornelia" sort="Van Duijn, Cornelia" uniqKey="Van Duijn C" first="Cornelia" last="Van Duijn">Cornelia Van Duijn</name></country><country name="Suisse"><region name="Canton de Zurich"><name sortKey="Jel I, Ilijas" sort="Jel I, Ilijas" uniqKey="Jel I I" first="Ilijas" last="Jel I">Ilijas Jel I</name></region><name sortKey="Martin, Roland" sort="Martin, Roland" uniqKey="Martin R" first="Roland" last="Martin">Roland Martin</name><name sortKey="Sospedra, Mireia" sort="Sospedra, Mireia" uniqKey="Sospedra M" first="Mireia" last="Sospedra">Mireia Sospedra</name></country><country name="Canada"><region name="Québec"><name sortKey="Lathrop, Mark" sort="Lathrop, Mark" uniqKey="Lathrop M" first="Mark" last="Lathrop">Mark Lathrop</name></region></country><country name="Nouvelle-Zélande"><noRegion><name sortKey="Mason, Deborah" sort="Mason, Deborah" uniqKey="Mason D" first="Deborah" last="Mason">Deborah Mason</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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